⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7962854 | 0.95 | — | — | |
| SCHEMBL19293661 | 0.80 | — | — | |
| SCHEMBL149335 | 0.74 | — | — | |
| SCHEMBL3204686 | 0.70 | — | — | |
| SCHEMBL24055070 | 0.70 | — | — | |
| SCHEMBL11881363 | 0.70 | — | — | |
| SCHEMBL5943518 | 0.70 | — | — | |
| SCHEMBL25433 | 0.67 | — | — | |
| SCHEMBL2803311 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL27620993 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016183101-A1 | PALLADIUM-CATALYZED ARYLATION OF FLUOROALKYLAMINES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-11-17 | — | — | WO | claimed |
| EP-1392693-B1 | TRIAZOLOPYRIMIDINES FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2007-02-07 | — | — | EP | claimed |
| US-20040176398-A1 | Triazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2004-09-09 | — | — | US | claimed |
| US-20040157863-A1 | Triazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2004-08-12 | — | — | US | claimed |
| US-20040142943-A1 | Triazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2004-07-22 | — | — | US | claimed |
| US-6265616-B1 | Manufacture of trifluorisopropylamine | HONEYWELL INTERNATIONAL INC. | 2001-07-24 | — | — | US | claimed |
| CN-118684662-A | Pyrrolopyridone-containing compounds | 正大天晴药业集团股份有限公司 | 2024-09-24 | — | — | CN | disclosed |
| CN-115572269-B | N-trifluoro isopropyl azole and indole compound and preparation method thereof | 广州大学 | 2024-05-17 | — | — | CN | disclosed |
| CN-109251158-B | Thioamidine amide compounds and use thereof for treating hepatitis B | 上海长森药业有限公司 | 2023-05-23 | — | — | CN | disclosed |
| US-11591334-B2 | Substituted pyrrolizines for the treatment of hepatitis B | SHANGHAI LONGWOOD BIOPHARMACEUTICALS CO., LTD. (CN) | 2023-02-28 | — | — | US | disclosed |
| CN-115572269-A | N-trifluoro isopropyl azole and indole compound and preparation method thereof | 广州大学 | 2023-01-06 | — | — | CN | disclosed |
| CN-108250122-B | Sulfonamide-aryl amide compounds and pharmaceutical use thereof for treating hepatitis B | 上海长森药业有限公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-110582500-B | Bicyclic nucleocapsid inhibitors and their use as medicaments for the treatment of hepatitis b | 上海长森药业有限公司 | 2022-04-05 | — | — | CN | disclosed |
| US-20040176398-A1 | Triazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2004-09-09 | — | — | US | disclosed |
| US-20040157863-A1 | Triazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2004-08-12 | — | — | US | disclosed |
| US-20040142943-A1 | Triazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2004-07-22 | — | — | US | disclosed |
| US-6265616-B1 | Manufacture of trifluorisopropylamine | HONEYWELL INTERNATIONAL INC. | 2001-07-24 | — | — | US | disclosed |
| US-6265616-B1 | Manufacture of trifluorisopropylamine | HONEYWELL INTERNATIONAL INC. | 2001-07-24 | — | — | US | disclosed |
| US-6204269-B1 | Fungicidal trifluoromethylalkylamino-triazolopyrimidines | AMERICAN CYANAMID CO. | 2001-03-20 | — | — | US | disclosed |
| US-5986135-A | CHEMICAL INTERMEDIATES | AMERICAN CYANAMID COMPANY (US) | 1999-11-16 | — | — | US | disclosed |