Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 15/20 | 0.80 |
| ▸ | CACNB1 | Q02641 | 15/20 | 0.80 |
| ▸ | CACNA1C | Q13936 | 11/20 | 0.80 |
| ▸ | CACNA1A | O00555 | 4/20 | 0.80 |
| ▸ | CACNA1B | Q00975 | 12/20 | 0.58 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.58 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4187829 | 0.90 | CACNA2D1 (0.97) | CACNA2D1CACNB1CACNA1CCACNA1ACACNA1B | |
| SCHEMBL4182908 | 0.82 | CACNA2D1 (1.00) | CACNA2D1CACNB1CACNA1CCACNA1ACACNA1B | |
| SCHEMBL8432816 | 0.82 | CACNA2D1 (0.71) | CACNA2D1CACNB1CACNA1CCACNA1ACACNA1B | |
| SCHEMBL5267208 | 0.82 | CACNA2D1 (0.71) | CACNA2D1CACNB1CACNA1CCACNA1ACACNA1B | |
| SCHEMBL5268878 | 0.82 | CACNA2D1 (0.64) | CACNA2D1CACNB1CACNA1CCACNA1ACACNA1B | |
| SCHEMBL13569214 | 0.81 | CACNA2D1 (0.70) | CACNA2D1CACNB1CACNA1CCACNA1ACACNA1B | |
| SCHEMBL5270987 | 0.79 | CACNA2D1 (0.67) | CACNA2D1CACNB1CACNA1CCACNA1ACACNA1B | |
| SCHEMBL5265057 | 0.79 | CACNA2D1 (0.67) | CACNA2D1CACNB1CACNA1CCACNA1ACACNA1B | |
| SCHEMBL8239769 | 0.77 | CACNA2D1 (0.75) | CACNA2D1CACNB1CACNA1CCACNA1ACACNA1B | |
| SCHEMBL27403138 | 0.75 | CACNA1A (0.49) | CACNA2D1CACNB1CACNA1CCACNA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1610792-B1 | CALCIUM CHANNEL BLOCKERS COMPRISING TWO BENZHYDRIL MOIETIES | NEUROMED TECH INC (CA) | 2007-10-10 | — | — | EP | claimed |