Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 17/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.66 |
| ▸ | CA1 | P00915 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 1/20 | 0.66 |
| ▸ | CA9 | Q16790 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3588135 | 0.86 | FAAH (1.00) | FAAHKDM4EMAPTNPC1TSHR | |
| SCHEMBL3595304 | 0.85 | FAAH (1.00) | FAAH | |
| SCHEMBL3596348 | 0.85 | FAAH (1.00) | FAAHKDM4EMAPTNPC1TSHR | |
| SCHEMBL3598643 | 0.84 | FAAH (1.00) | FAAHKDM4EMAPTNPC1TSHR | |
| SCHEMBL3598540 | 0.84 | FAAH (0.78) | FAAHKDM4EMAPTNPC1TSHR | |
| SCHEMBL3598088 | 0.83 | FAAH (1.00) | FAAHKDM4EMAPTNPC1TSHR | |
| SCHEMBL3604165 | 0.83 | FAAH (1.00) | FAAHKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL3602524 | 0.83 | FAAH (1.00) | FAAHKDM4EMAPT | |
| SCHEMBL3601788 | 0.81 | FAAH (1.00) | FAAH | |
| SCHEMBL3593916 | 0.81 | FAAH (1.00) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836179-A1 | PIPERAZINYL AND PIPERIDINYL UREAS AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006074025-A1 | PIPERAZINYL AND PIPERIDINYL UREAS AS MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-07-13 | — | — | WO | disclosed |