Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR34 | Q9UPC5 | 5/20 | 0.54 |
| ▸ | CDK2 | P24941 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.45 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | YAP1 | P46937 | 2/20 | 0.44 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3498698 | 0.94 | GPR34 (0.54) | GPR34CDK2PPARGRAB9AGAA | |
| SCHEMBL3499082 | 0.94 | GPR34 (0.54) | GPR34CDK2PPARGRAB9AGAA | |
| SCHEMBL3499160 | 0.94 | GPR34 (0.63) | GPR34PPARGPTPN1KMT2AADAMTS4 | |
| SCHEMBL3499163 | 0.94 | GPR34 (0.63) | GPR34PPARGPTPN1KMT2AADAMTS4 | |
| SCHEMBL3498316 | 0.90 | CDK2 (0.46) | GPR34CDK2PPARGSLC26A4KMT2A | |
| SCHEMBL3498317 | 0.90 | CDK2 (0.46) | GPR34CDK2PPARGSLC26A4KMT2A | |
| SCHEMBL3498196 | 0.87 | GPR34 (0.63) | GPR34PPARGPTPN1KMT2AADAMTS4 | |
| SCHEMBL3499991 | 0.87 | GPR34 (0.63) | GPR34PPARGPTPN1KMT2AADAMTS4 | |
| SCHEMBL13344477 | 0.87 | GPR34 (0.63) | GPR34PPARGPTPN1KMT2AADAMTS4 | |
| SCHEMBL3500625 | 0.86 | GPR34 (0.49) | GPR34CDK2PPARGRAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1849465-A1 | AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR | Takeda Pharmaceutical Company Limited (JP) | 2007-10-31 | — | — | EP | disclosed |