SCHEMBL52703

SCHEMBL52703

C=C(CO)C(=O)OCCC

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.44
THRB P10828 1/20 0.41
HCAR2 Q8TDS4 1/20 0.38
ALDH1A1 P00352 5/20 0.36
GAA P10253 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
LMNA P02545 2/20 0.35
ESR1 P03372 1/20 0.34
CHRM1 P11229 1/20 0.34
SLC6A2 P23975 1/20 0.34
KDR P35968 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
HPGD P15428 1/20 0.33
ATM Q13315 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GLA P06280 1/20 0.31
ACHE P22303 1/20 0.31
NAAA Q02083 1/20 0.30
DGKA P23743 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26129017 1.00 TSHR (0.44) TSHRTHRBHCAR2ALDH1A1GAA
Phosphoric Acid SCHEMBL15156944 0.92 TSHR (0.39) TSHRTHRBHCAR2ALDH1A1GAA
Acrylic Acid SCHEMBL9248645 0.89 HCAR2 (0.43) TSHRTHRBHCAR2ALDH1A1GAA
SCHEMBL3255275 0.87 ALDH1A1 (0.38) TSHRTHRBHCAR2ALDH1A1GAA
SCHEMBL15788931 0.87 TSHR (0.66) TSHRTHRBALDH1A1TDP1HPGD
SCHEMBL26126122 0.87 TSHR (0.55) TSHRTHRBHCAR2ALDH1A1SMN1; SMN2
SCHEMBL198447 0.87 TSHR (0.55) TSHRTHRBHCAR2ALDH1A1SMN1; SMN2
SCHEMBL3788731 0.85 TSHR (0.63) TSHRHCAR2ALDH1A1LMNAHPGD
SCHEMBL3478021 0.84 TSHR (0.45) TSHRTHRBHCAR2ALDH1A1GAA
SCHEMBL5085052 0.84 TSHR (0.67) TSHRHCAR2ALDH1A1LMNAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8365 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118325267-A Preparation method and application of functionalized polyionic liquid ionic gel electrolyte 湖北工程学院 2024-07-12 CN claimed
CN-118307709-A Fluoropolymer, aqueous primer slurry, secondary battery, and electric device 宁德时代新能源科技股份有限公司 2024-07-09 CN claimed
US-20240222122-A1 ADHESION LAYERS FOR EUV LITHOGRAPHY BREWER SCIENCE, INC. 2024-07-04 US claimed
CN-118184951-A Polyurethane modified epoxy acrylate resin and preparation method and application thereof 深圳市墨库新材料集团股份有限公司 2024-06-14 CN claimed
CN-118085296-A Organosilicon modified polymer and preparation method and application thereof 广东标美硅氟新材料有限公司 2024-05-28 CN claimed
US-11972948-B2 Adhesion layers for EUV lithography BREWER SCIENCE, INC. (US) 2024-04-30 US claimed
CN-117925067-A Durable multifunctional coating and preparation method and application thereof 广西电网有限责任公司电力科学研究院 2024-04-26 CN claimed
CN-117866149-A Photosensitive resin composition based on ionic liquid and application of photosensitive resin composition in 405nm3D printing 福州大学 2024-04-12 CN claimed
CN-117457259-B UV-cured conductive silver paste with good flexibility and preparation method thereof 深圳市通泰盈科技股份有限公司 2024-03-22 CN claimed
CN-117720687-A Repairable polyurethane photosensitive resin composition and application thereof in 405nm photocuring 3D printing 泉州师范学院 2024-03-19 CN claimed
US-4120721-A ACRYLIC OR METHACRYLIC TERMINATED, URETHANE CONTAINING POLYENE; WATER INSOLUBLE VINYL MONOMER DILUENT; POLYTHIOL; PHOTOINITIATOR W. R. GRACE & CO. (US) 1978-10-17 US claimed
US-4106955-A ADDITION POLYMERIZATION, GRAFT POLYMERIZATION GULF & WESTERN MANUFACTURING COMPANY (US) 1978-08-15 US claimed
US-4107114-A MIXTURE OF MONOETHYLENICALLY AND POLYETHYLENICALLY UNSATURATED MONOMERS AND EMULSIFIER KANSAI PAINT COMPANY, LIMITED (JP) 1978-08-15 US claimed
US-4089844-A INTERNAL PLASTICIZER GROW CHEMICAL CORP. (US) 1978-05-16 US claimed
US-3998768-A Thermosetting powder coating composition of a blend of acrylic polymers having different glass transition temperatures and a blocked polyisocyanate cross-linking agent E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-12-21 US claimed
US-3998997-A Pressure sensitive adhesives using interpolymer of acrylates, oxypropyl acrylamides and acrylic acid THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-12-21 US claimed
US-3993849-A Metal substrate coated with a thermosetting powder coating composition of an acrylic polymer, a hydroxy functional plasticizer and a blocked polyisocyanate cross-linking agent E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-11-23 US claimed
US-3991226-A Method of creating an image using hybrid liquid toners PHILIP A. HUNT CHEMICAL CORPORATION (US) 1976-11-09 US claimed
US-3990980-A Hybrid liquid toners PHILIP A. HUNT CHEMICAL CORPORATION (US) 1976-11-09 US claimed
US-3947401-A Hydrogels of unsaturated ester copolymers UNION OPTICS CORPORATION (US) 1976-03-30 US claimed