Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ACLY | P53396 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.45 |
| ▸ | CPT1A | P50416 | 2/20 | 0.45 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.45 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5271640 | 0.85 | KCNA5 (0.51) | MEN1KMT2AMAPTACLYMCL1 | |
| SCHEMBL5270409 | 0.84 | MCL1 (0.52) | ACLYMCL1MAPK1HPGDTSHR | |
| SCHEMBL5271604 | 0.84 | MEN1 (0.55) | MEN1KMT2AGRM4HPGDALDH1A1 | |
| SCHEMBL5268776 | 0.83 | CCKAR (0.52) | MEN1KMT2AMAPTACLYMCL1 | |
| SCHEMBL5269293 | 0.83 | MCL1 (0.50) | MEN1KMT2AMAPTACLYMCL1 | |
| SCHEMBL5270764 | 0.81 | KMT2A (0.52) | MEN1KMT2AGRM4HPGDALDH1A1 | |
| SCHEMBL5271647 | 0.79 | MCL1 (0.46) | ACLYMCL1MAPK1HPGDTSHR | |
| SCHEMBL5273547 | 0.78 | TSHR (0.49) | MEN1KMT2AACLYTSHRALDH1A1 | |
| SCHEMBL5269115 | 0.77 | HPGD (0.48) | MEN1KMT2AMAPTMAPK1HPGD | |
| SCHEMBL5269316 | 0.77 | CSNK2A1 (0.52) | MEN1KMT2AMAPK1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847531-A1 | PYRAZOLE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2007-10-24 | — | — | EP | disclosed |