Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.68 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.68 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4262215 | 1.00 | TAS1R3 (0.68) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4261765 | 0.99 | TAS1R3 (0.67) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL5270953 | 0.98 | TAS1R3 (0.66) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL4262863 | 0.94 | TAS1R3 (0.59) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4259276 | 0.93 | TAS1R3 (0.58) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL5923948 | 0.88 | KMT2A (0.81) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL5275903 | 0.88 | KMT2A (0.81) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL5275894 | 0.88 | KMT2A (0.81) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL701117 | 0.81 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL5923959 | 0.81 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848289-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | Senomyx, Inc. (US) | 2007-10-31 | — | — | EP | claimed |
| WO-2006084246-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2006-08-10 | — | — | WO | claimed |
| US-20060045953-A1 | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers | SENOMYX, INC. | 2006-03-02 | — | — | US | claimed |