Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.72 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.72 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5273146 | 1.00 | TAS1R3 (0.72) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL5269874 | 0.95 | TAS1R3 (0.75) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL5269869 | 0.95 | TAS1R3 (0.75) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL5271096 | 0.91 | TAS1R3 (0.77) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL5271097 | 0.91 | TAS1R3 (0.77) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL5394823 | 0.84 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL701644 | 0.84 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL5923920 | 0.77 | TAS1R3 (0.87) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL704770 | 0.76 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL5923958 | 0.76 | TAS1R3 (0.84) | TAS1R3TAS1R1TAS1R2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848289-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | Senomyx, Inc. (US) | 2007-10-31 | — | — | EP | claimed |
| WO-2006084246-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2006-08-10 | — | — | WO | claimed |
| US-20060045953-A1 | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers | SENOMYX, INC. | 2006-03-02 | — | — | US | claimed |
| US-20060045953-A1 | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers | SENOMYX, INC. | 2006-03-02 | — | — | US | disclosed |