SCHEMBL5273635

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5210378	0.95	CYP1A2 (0.51)	CYP1A2LOXL2KMT2AMEN1SMN1; SMN2
	SCHEMBL7832661	0.94	MAPT (0.51)	CYP1A2LOXL2LTB4R
	SCHEMBL7829170	0.94	MAPT (0.51)	CYP1A2LOXL2LTB4R
	SCHEMBL1650885	0.90	CYP1A2 (0.55)	CYP1A2LOXL2KMT2ASMN1; SMN2HDAC6
	SCHEMBL30684525	0.89	CHRM1 (0.56)	KMT2AMEN1SMN1; SMN2HTTCHRM1
	SCHEMBL21820732	0.86	LOXL2 (0.49)	CYP1A2LOXL2KMT2AMEN1HDAC3
	Trifluoroacetic Acid SCHEMBL2846592	0.83	CYP1A2 (0.49)	CYP1A2LOXL2KMT2AHDAC6CHRM1
	SCHEMBL7992922	0.83	MEN1 (0.48)	CYP1A2KMT2AMEN1SMN1; SMN2HDAC3
	SCHEMBL17537572	0.82	HDAC3 (0.63)	CYP1A2KMT2AMEN1SMN1; SMN2HDAC3
	SCHEMBL8496699	0.81	HTT (0.44)	KMT2AMEN1SMN1; SMN2HDAC3MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.