Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | ICMT | O60725 | 14/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | FNTA | P49354 | 1/20 | 0.56 |
| ▸ | FNTB | P49356 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5423426 | 1.00 | MAPT (1.00) | MAPTALDH1A1ICMTMEN1TRPA1 | |
| SCHEMBL8025173 | 1.00 | MAPT (1.00) | MAPTALDH1A1ICMTMEN1TRPA1 | |
| SCHEMBL2818645 | 1.00 | MAPT (1.00) | MAPTALDH1A1ICMTMEN1TRPA1 | |
| SCHEMBL5433147 | 1.00 | MAPT (1.00) | MAPTALDH1A1ICMTMEN1TRPA1 | |
| SCHEMBL664393 | 1.00 | MAPT (1.00) | MAPTALDH1A1ICMTMEN1TRPA1 | |
| SCHEMBL1648111 | 1.00 | MAPT (1.00) | MAPTALDH1A1ICMTMEN1TRPA1 | |
| SCHEMBL4024890 | 1.00 | MAPT (1.00) | MAPTALDH1A1ICMTMEN1TRPA1 | |
| SCHEMBL2818639 | 1.00 | MAPT (1.00) | MAPTALDH1A1ICMTMEN1TRPA1 | |
| SCHEMBL1648108 | 1.00 | MAPT (1.00) | MAPTALDH1A1ICMTMEN1TRPA1 | |
| SCHEMBL1762100 | 0.99 | MAPT (0.97) | MAPTALDH1A1ICMTMEN1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009833-B1 | PRENYLCYSTEINE CARBOXYL METHYL-TRANSFERASE, DNA ENCONDING SAME, AND A METHOD OF SCREENING FOR INHIBITORS THEREOF | UNIV NEW YORK (US) | 2007-12-12 | — | — | EP | disclosed |
| US-6432403-B1 | INHIBITORS OF CARBOXYL METHYLATION IN TREATMENT OF INFLAMMATION AND CANCER; SPECIFIC FOR AN EPITOPE OF THE PROTEIN CONSISTING OF THE AMINO ACID SEQUENCE OF SEQ ID NO:5 | NEW YORK UNIVERSITY | 2002-08-13 | — | — | US | disclosed |
| US-6184016-B1 | AMINO ACID SEQUENCE OF ENZYME INVOLVED IN POST-TRANSLATIONAL MODIFICATION OF PRENYLATED PROTEINS; FOR SCREENING OF ENZYME INHIBITORS; ANTIINFLAMMATORY/ANTICARCINOGENIC AGENTS | NEW YORK UNIVERSITY | 2001-02-06 | — | — | US | disclosed |