SCHEMBL2818639

SCHEMBL2818639

CC(=O)N[C@@H](CSC/C=C(\C)CC/C=C(\C)CCC=C(C)C)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 1.00
ALDH1A1 P00352 1/20 1.00
ICMT O60725 14/20 0.67
MEN1 O00255 1/20 0.61
TRPA1 O75762 1/20 0.61
KMT2A Q03164 1/20 0.61
FNTA P49354 1/20 0.56
FNTB P49356 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5423426 1.00 MAPT (1.00) MAPTALDH1A1ICMTMEN1TRPA1
SCHEMBL8025173 1.00 MAPT (1.00) MAPTALDH1A1ICMTMEN1TRPA1
SCHEMBL2818645 1.00 MAPT (1.00) MAPTALDH1A1ICMTMEN1TRPA1
SCHEMBL5433147 1.00 MAPT (1.00) MAPTALDH1A1ICMTMEN1TRPA1
SCHEMBL664393 1.00 MAPT (1.00) MAPTALDH1A1ICMTMEN1TRPA1
SCHEMBL5274733 1.00 MAPT (1.00) MAPTALDH1A1ICMTMEN1TRPA1
SCHEMBL1648111 1.00 MAPT (1.00) MAPTALDH1A1ICMTMEN1TRPA1
SCHEMBL4024890 1.00 MAPT (1.00) MAPTALDH1A1ICMTMEN1TRPA1
SCHEMBL1648108 1.00 MAPT (1.00) MAPTALDH1A1ICMTMEN1TRPA1
SCHEMBL1762100 0.99 MAPT (0.97) MAPTALDH1A1ICMTMEN1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12036245-B2 Pharmaceutical composition and cosmetic composition I PEACE, INC. (US) 2024-07-16 US claimed
US-20240099944-A1 Stable Skin Care Compositions Containing a Retinoid THE PROCTER & GAMBLE COMPANY 2024-03-28 US claimed
US-20170157170-A1 COMPOSITIONS CONTAINING POLYMERIC SULFUR AND USES THEREOF KENVUE BRANDS LLC 2017-06-08 US claimed
EP-3175888-A1 COMPOSITIONS CONTAINING POLYMERIC SULFUR AND USES THEREOF Johnson & Johnson Consumer Inc. (US) 2017-06-07 EP claimed
US-20260057182-A1 Graphics-Informed Data-Contextual Report Compilation via Automated Point-of-Interest Detection in Visualization Inventories PONTIMYX CORP (US) 2026-02-26 US disclosed
US-20250339471-A1 PHARMACEUTICAL COMPOSITION AND COSMETIC COMPOSITION I PEACE, INC. (US) 2025-11-06 US disclosed
US-12456017-B2 Interactive neural-symbolic orchestration of subjective stored procedures PONTIMYX CORP (US) 2025-10-28 US disclosed
US-20250302710-A1 SKIN CARE COMPOSITIONS CONTAINING A RETINOID WITH REDUCED MALODOR THE PROCTER & GAMBLE COMPANY 2025-10-02 US disclosed
US-12383583-B2 Pharmaceutical composition and cosmetic composition I PEACE, INC. (US) 2025-08-12 US disclosed
US-20250165717-A1 Multilevel Data Analysis PONTIMYX CORP (US) 2025-05-22 US disclosed
US-12210839-B1 Multilevel data analysis Pontimyx Corporation 2025-01-28 US disclosed
US-20240316117-A1 PHARMACEUTICAL COMPOSITION AND COSMETIC COMPOSITION I PEACE, INC. (US) 2024-09-26 US disclosed
US-20030228688-A1 Antisense modulation of isoprenylcysteine carboxyl methyltransferase expression ISIS PHARMACEUTICALS INC. 2003-12-11 US disclosed
US-6432403-B1 INHIBITORS OF CARBOXYL METHYLATION IN TREATMENT OF INFLAMMATION AND CANCER; SPECIFIC FOR AN EPITOPE OF THE PROTEIN CONSISTING OF THE AMINO ACID SEQUENCE OF SEQ ID NO:5 NEW YORK UNIVERSITY 2002-08-13 US disclosed
US-6232108-B1 RECOMBINANT DNA CODING FOR ENZYME OF DEFINED AMINO ACID SEQUENCE WHICH IS INVOLVED IN FURTHER POST-TRANSLATIONAL PROCESSING OF PRENYLATED PROTEINS; DRUG SCREENING OF ANTICARCINOGENIC AND ANTINFLAMMATORY AGENTS NEW YORK UNIVERSITY 2001-05-15 US disclosed
US-6184016-B1 AMINO ACID SEQUENCE OF ENZYME INVOLVED IN POST-TRANSLATIONAL MODIFICATION OF PRENYLATED PROTEINS; FOR SCREENING OF ENZYME INHIBITORS; ANTIINFLAMMATORY/ANTICARCINOGENIC AGENTS NEW YORK UNIVERSITY 2001-02-06 US disclosed
US-6015877-A ANTICARCINOGENIC AGENT WHICH INHIBITS ENDOPROTEASE ACTIVITY DIRECTED AGAINST SPECIFIC CYSTEINE CONTAINING CARBOXY TERMINAL MOTIF FOUND IN RAS PROTEINS AND OTHER SIGNAL TRANSDUCING G PROTEINS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2000-01-18 US disclosed
US-5789541-A ENZYME INHIBITORS, FARNESYL OR GERANYL GROUPS, CONTROLLING NEOPLASTIC CELL GROWTH, ANTITUMOR, ANTICARCINOGENIC AGENTS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1998-08-04 US disclosed
US-5202456-A Anticarcinogenic agents; methylating transferase inhibitors; farnesyl or geranyl sulfur-, oxygen or selenium-containing derivatives THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1993-04-13 US disclosed
WO-1992018465-A2 COMPOUNDS FOR INHIBITION OF PROTEIN METHYLATION THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1992-10-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260057182-A1 Graphics-Informed Data-Contextual Report Compilation via Automated Point-of-Interest Detection in Visualization Inventories NOTCH1, NOTCH4, DNER MAPT 720/4885ALDH1A1 4058/4885ICMT 3118/4885
US-20250302710-A1 SKIN CARE COMPOSITIONS CONTAINING A RETINOID WITH REDUCED MALODOR RBP4, RARA, RBP1 MAPT 1006/4885ALDH1A1 20/4885ICMT 1638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.