SCHEMBL527476

SCHEMBL527476

CCCCCCCCCCCCCCCC([C]=O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.59
GPR84 Q9NQS5 7/20 0.55
FFAR1 O14842 2/20 0.55
LCK P06239 1/20 0.53
PPARD Q03181 1/20 0.53
ZDHHC20 Q5W0Z9 1/20 0.53
ZDHHC2 Q9UIJ5 1/20 0.53
ACE2 Q9BYF1 1/20 0.50
GRIK1 P39086 2/20 0.46
GRIK2 Q13002 2/20 0.46
FFAR4 Q5NUL3 1/20 0.46
SLC1A2 P43004 1/20 0.43
SLC1A1 P43005 1/20 0.43
CA2 P00918 1/20 0.42
HSPD1 P10809 1/20 0.42
BLM P54132 1/20 0.42
HSPE1 P61604 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL970515 1.00 MAPT (0.59) MAPTGPR84FFAR1LCKPPARD
SCHEMBL7207894 1.00 MAPT (0.59) MAPTGPR84FFAR1LCKPPARD
SCHEMBL10923278 1.00 MAPT (0.59) MAPTGPR84FFAR1LCKPPARD
SCHEMBL4002470 1.00 MAPT (0.59) MAPTGPR84FFAR1LCKPPARD
SCHEMBL6539103 0.98 MAPT (0.55) MAPTGPR84FFAR1LCKPPARD
SCHEMBL1401236 0.91 CA2 (0.50) MAPTGPR84FFAR1LCKPPARD
SCHEMBL5158482 0.83 MAPT (0.48) MAPTGPR84FFAR1LCKPPARD
SCHEMBL11329644 0.83 MAPT (0.48) MAPTGPR84FFAR1LCKPPARD
SCHEMBL8458707 0.83 MAPT (0.48) MAPTGPR84FFAR1LCKPPARD
SCHEMBL3127134 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 423 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3065767-B1 GIP-GLP-1 DUAL AGONIST COMPOUNDS AND METHODS ZEALAND PHARMA AS (DK) 2020-12-30 EP claimed
US-20190218270-A1 GIP-GLP-1 DUAL AGONIST COMPOUNDS AND METHODS ZEALAND PHARMA A/S (DK) 2019-07-18 US claimed
US-20160280754-A1 GIP-GLP-1 DUAL AGONIST COMPOUNDS AND METHODS ZEALAND PHARMA A/S (DK) 2016-09-29 US claimed
EP-3065767-A2 GIP-GLP-1 DUAL AGONIST COMPOUNDS AND METHODS Zealand Pharma A/S (DK) 2016-09-14 EP claimed
WO-2015067715-A2 GIP-GLP-1 DUAL AGONIST COMPOUNDS AND METHODS ZEALAND PHARMA A/S (DK) 2015-05-14 WO claimed
EP-1517697-A1 ACIDIC INSULIN PREPARATIONS WITH IMPROVED STABILITY Aventis Pharma Deutschland GmbH (DE) 2005-03-30 EP claimed
EP-1381385-A1 INSULIN PREPARATIONS, WHICH DO NOT CONTAIN ANY ZINC OR ONLY A SMALL QUANTITY OF ZINC AND WHICH HAVE AN IMPROVED STABILITY Aventis Pharma Deutschland GmbH (DE) 2004-01-21 EP claimed
WO-2003105888-A1 ACIDIC INSULIN PREPARATIONS WITH IMPROVED STABILITY AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2003-12-24 WO claimed
WO-2002076495-A1 INSULIN PREPARATIONS, WHICH DO NOT CONTAIN ANY ZINC OR ONLY A SMALL QUANTITY OF ZINC AND WHICH HAVE AN IMPROVED STABILITY AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2002-10-03 WO claimed
EP-1121145-A1 INSULIN PREPARATIONS FOR PULMONARY DELIVERY CONTAINING MENTHOL Novo Nordisk A/S (DK) 2001-08-08 EP claimed
EP-1121144-A1 STABLE CONCENTRATED INSULIN PREPARATIONS FOR PULMONARY DELIVERY Novo Nordisk A/S (DK) 2001-08-08 EP claimed
WO-2000023099-A1 INSULIN PREPARATIONS FOR PULMONARY DELIVERY CONTAINING MENTHOL NOVO NORDISK A/S (DK) 2000-04-27 WO claimed
WO-2000023098-A1 STABLE CONCENTRATED INSULIN PREPARATIONS FOR PULMONARY DELIVERY NOVO NORDISK A/S (DK) 2000-04-27 WO claimed
EP-4297830-A1 FLUID DISPENSING DEVICE Sanofi (FR) 2024-01-03 EP disclosed
EP-4252248-A1 CLASSIFYING IMAGES OF DOSE-RESPONSE GRAPHS Sanofi (FR) 2023-10-04 EP disclosed
EP-4222756-A1 METHODS AND SYSTEMS FOR TRACKING DOSAGE INFORMATION OF ELECTRONICALLY ENABLED INJECTION DEVICES Sanofi (FR) 2023-08-09 EP disclosed
EP-0969860-A1 METHOD FOR PREPARATION OF A THERAPEUTIC POWDER THROUGH COPRECIPITATION OF INSULIN AND ABSORPTION ENHANCER NOVO NORDISK A/S (DK) 2000-01-12 EP disclosed
WO-1999034821-A1 STABILISED INSULIN COMPOSITIONS NOVO NORDISK A/S (DK) 1999-07-15 WO disclosed
WO-1998042367-A1 METHOD FOR PREPARATION OF A THERAPEUTIC POWDER THROUGH COPRECIPITATION OF INSULIN AND ABSORPTION ENHANCER NOVO NORDISK A/S (DK) 1998-10-01 WO disclosed
WO-1998042368-A1 THERAPEUTIC POWDER FORMULATION FOR PULMONARY ADMINISTRATION, CONTAINING CRYSTALLINE INSULIN NOVO NORDISK A/S (DK) 1998-10-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160280754-A1 GIP-GLP-1 DUAL AGONIST COMPOUNDS AND METHODS GLP1R, GIPR, GCGR MAPT 4780/4885GPR84 100/4885FFAR1 142/4885
US-20190218270-A1 GIP-GLP-1 DUAL AGONIST COMPOUNDS AND METHODS GLP1R, GIPR, GCGR MAPT 4780/4885GPR84 100/4885FFAR1 142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.