SCHEMBL5276295

SCHEMBL5276295

O=C(CCl)c1cc(Cl)cc(Cl)c1

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 9/20 0.60
TPMT P51580 1/20 0.54
ALDH1A1 P00352 3/20 0.50
HIF1A Q16665 3/20 0.50
MAPK1 P28482 2/20 0.50
TRPA1 O75762 1/20 0.50
RAB9A P51151 1/20 0.47
FABP4 P15090 1/20 0.44
HCAR1 Q9BXC0 1/20 0.41
TSHR P16473 1/20 0.40
TP53 P04637 1/20 0.39
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2450506 0.85 GSK3B (0.50) GSK3BTPMTALDH1A1HIF1AMAPK1
SCHEMBL29334169 0.85 GSK3B (0.50) GSK3BTPMTALDH1A1HIF1AMAPK1
SCHEMBL1448228 0.80 TPMT (0.54) GSK3BTPMTRAB9AFABP4HCAR1
SCHEMBL2448703 0.79 CYP3A4 (0.46) GSK3BALDH1A1TSHRTP53
SCHEMBL10498599 0.78 GSK3B (0.52) GSK3BALDH1A1HIF1AMAPK1TRPA1
SCHEMBL10387740 0.78 TPMT (0.52) GSK3BTPMTALDH1A1RAB9AFABP4
SCHEMBL1198757 0.78 GSK3B (0.61) GSK3BTPMTRAB9AFABP4HCAR1
SCHEMBL633305 0.78 TPMT (0.52) TPMTALDH1A1RAB9AFABP4HCAR1
SCHEMBL15189680 0.78 TPMT (0.52) GSK3BTPMTALDH1A1RAB9AFABP4
SCHEMBL4565219 0.78 ERCC5 (0.62) GSK3BALDH1A1HIF1AMAPK1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116943408-B Hindered amine composite desulfurizing agent and preparation method thereof 江苏创新石化有限公司 2024-01-30 CN claimed
CN-116943408-A Hindered amine composite desulfurizing agent and preparation method thereof 江苏创新石化有限公司 2023-10-27 CN claimed
EP-1349823-B1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR CHEMTURA CORP (US) 2007-11-21 EP claimed
EP-1349823-A1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR Crompton Corporation (US) 2003-10-08 EP claimed
WO-2002055466-A1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR CROMPTON CORPORATION (US) 2002-07-18 WO claimed
US-6410795-B1 FORMING DIKETONES CROMPTON CORPORATION 2002-06-25 US claimed
CN-116943408-B Hindered amine composite desulfurizing agent and preparation method thereof 江苏创新石化有限公司 2024-01-30 CN disclosed
CN-116943408-A Hindered amine composite desulfurizing agent and preparation method thereof 江苏创新石化有限公司 2023-10-27 CN disclosed
EP-1349823-B1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR CHEMTURA CORP (US) 2007-11-21 EP disclosed
EP-1349823-A1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR Crompton Corporation (US) 2003-10-08 EP disclosed
WO-2002055466-A1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR CROMPTON CORPORATION (US) 2002-07-18 WO disclosed
US-6410795-B1 FORMING DIKETONES CROMPTON CORPORATION 2002-06-25 US disclosed
EP-0507013-B1 Process for the preparation of aromatic beta-diketones WITCO CORP (US) 1996-02-07 EP disclosed
EP-0507013-A1 Process for the preparation of aromatic beta-diketones WITCO CORPORATION (US) 1992-10-07 EP disclosed
US-5015777-A Reaction of an acetophenone and an aliphatic ester or an ester of benzoic acid in the presence of sodium alkoxide condensation agent in an aromatic solvent WITCO CORPORATION (US) 1991-05-14 US disclosed