Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GRN | P28799 | 2/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1260276 | 0.87 | HCAR1 (0.59) | TPMTRAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL19137597 | 0.87 | GPR139 (0.42) | TPMTRAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL11342136 | 0.87 | TSHR (0.42) | TPMTRAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL12780435 | 0.86 | TAS1R3 (0.43) | TPMTRAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL30512212 | 0.86 | TAS1R3 (0.43) | TPMTRAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL27915406 | 0.82 | DDR1 (0.46) | SMN1; SMN2MEN1KMT2ABAZ2BBAZ2A | |
| SCHEMBL11382828 | 0.82 | MAPT (0.50) | MAPTSMN1; SMN2L3MBTL1PPARAMEN1 | |
| SCHEMBL10412858 | 0.81 | TPMT (0.35) | TPMTRAB9AMAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL27873685 | 0.81 | DDR1 (0.48) | PPARAMEN1CYP3A4KMT2AGAA | |
| SCHEMBL28277550 | 0.79 | PPARA (0.47) | MAPTSMN1; SMN2L3MBTL1PPARAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111212830-B | N- (substituted sulfonyl) benzamide derivative and preparation method and medical application thereof | 浙江海正药业股份有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-113234062-B | Pyrazinylimidazole compound, weldable protective agent, preparation method and application of pyrazinylimidazole compound and weldable protective agent | 赣州市贝加尔电子材料有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-113234062-A | Pyrazinylimidazole compound, weldable protective agent, preparation method and application of pyrazinylimidazole compound and weldable protective agent | 赣州市贝加尔电子材料有限公司 | 2021-08-10 | — | — | CN | disclosed |
| US-10919841-B2 | Monoamine reuptake inhibitors | RESEARCH TRIANGLE INSTITUTE (US) | 2021-02-16 | — | — | US | disclosed |
| CN-111212830-A | N- (substituted sulfonyl) benzamide derivative and preparation method and medical application thereof | 浙江海正药业股份有限公司 | 2020-05-29 | — | — | CN | disclosed |
| CN-106165684-B | Pesticidal compositions and methods relating thereto | 陶氏益农公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-105153235-B | Phosphor material | 通用显示公司 | 2019-05-10 | — | — | CN | disclosed |
| WO-2019062848-A1 | N-(SUBSTITUTED SULFONYL)BENZAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF | 浙江海正药业股份有限公司 | 2019-04-04 | — | — | WO | disclosed |
| CN-105025715-B | Pesticidal compositions and methods related thereto | 美国陶氏益农公司 | 2018-11-16 | — | — | CN | disclosed |
| CN-108495851-A | Substituted benzamide and its application method | 基因泰克公司 | 2018-09-04 | — | — | CN | disclosed |
| US-20120070409-A1 | TETRACYCLIC FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR | JAPAN TOBACCO INC. (JP) | 2012-03-22 | — | — | US | disclosed |
| EP-2419400-A1 | MONOAMINE REUPTAKE INHIBITORS | RESEARCH TRIANGLE INSTITUTE (US) | 2012-02-22 | — | — | EP | disclosed |
| US-20120020920-A1 | 5-5-MEMBERED FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR | JAPAN TOBACCO INC. (JP) | 2012-01-26 | — | — | US | disclosed |
| WO-2011146821-A2 | 1 - PHENYLMORPHOLINE DERIVATIVES AS HYDROXYBUPROPION ANALOGUES FOR TREATING DRUG DEPENDENCE | RESEARCH TRIANGLE INSTITUTE (US) | 2011-11-24 | — | — | WO | disclosed |
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |
| WO-2010121022-A1 | MONOAMINE REUPTAKE INHIBITORS | RESEARCH TRIANGLE INSTITUTE (US) | 2010-10-21 | — | — | WO | disclosed |
| CN-101657518-A | phosphorescent material | UNIV DISPLAY CORP US | 2010-02-24 | — | — | CN | disclosed |
| US-7645771-B2 | CCR5 antagonists as therapeutic agents | SMITHKLINE BEECHAM CORP. (US) | 2010-01-12 | — | — | US | disclosed |
| CN-1063440-C | Process for the desulfurization and the desalting of fossil fuels | RHONE ROULENC AGROCHIMIE CORP (FR) | 2001-03-21 | — | — | CN | disclosed |
| CN-1079735-A | Arylpyrazole mycocide | ENERGY BIOSYSTEMS CORP (FR) | 1993-12-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120020920-A1 | 5-5-MEMBERED FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR | GTF3C5, ZC3HAV1, POLI | TPMT 132/4885RAB9A 1530/4885MAPT 4033/4885 |
| US-10919841-B2 | Monoamine reuptake inhibitors | SLC6A2, SLC6A4, SLC6A3 | TPMT 1838/4885RAB9A 2855/4885MAPT 440/4885 |
| US-20120070409-A1 | TETRACYCLIC FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR | POLI, TERT, ZC3HAV1 | TPMT 33/4885RAB9A 2410/4885MAPT 3389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.