Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.46 |
| ▸ | SLC9A1 | P19634 | 4/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5282168 | 0.92 | SLC9A1 (0.46) | GRM2SLC9A1TOP2AHCAR3ALDH1A1 | |
| SCHEMBL5280505 | 0.88 | GRM2 (0.43) | GRM2SLC9A1TOP2AKMT2AHCAR3 | |
| SCHEMBL5280549 | 0.82 | GRM2 (0.47) | GRM2SLC9A1TOP2AKMT2AHCAR3 | |
| SCHEMBL5277654 | 0.79 | SLC9A1 (0.46) | GRM2SLC9A1TOP2AKMT2AHCAR3 | |
| SCHEMBL5279841 | 0.79 | — | — | |
| SCHEMBL5280700 | 0.78 | GRM2 (0.45) | GRM2SLC9A1TOP2AKMT2AHCAR3 | |
| SCHEMBL5278898 | 0.78 | GRM2 (0.45) | GRM2SLC9A1TOP2AKMT2AHCAR3 | |
| SCHEMBL5283304 | 0.78 | GRM2 (0.45) | GRM2SLC9A1TOP2AKMT2AHCAR3 | |
| SCHEMBL5278986 | 0.77 | GRM2 (0.44) | GRM2SLC9A1TOP2AKMT2AHCAR3 | |
| SCHEMBL5282462 | 0.77 | GRM2 (0.44) | GRM2SLC9A1TOP2AKMT2AHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859781-A2 | Brightening and/or colouring agent with triazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |