Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750315 | 0.94 | HCAR2 (0.36) | HCAR2HCAR3 | |
| SCHEMBL17950108 | 0.81 | KDM4E (0.37) | HRH3KDM4E | |
| Hydrochloric Acid SCHEMBL17941984 | 0.79 | KDM4E (0.36) | KDM4E | |
| SCHEMBL5276698 | 0.78 | HCAR2 (0.44) | HCAR2HCAR3HRH3PBRM1 | |
| SCHEMBL21573787 | 0.78 | KDM4E (0.41) | KDM4E | |
| SCHEMBL5276881 | 0.77 | HCAR2 (0.42) | HCAR2HCAR3HRH3 | |
| SCHEMBL5279145 | 0.77 | HCAR2 (0.42) | HCAR2HCAR3HRH3 | |
| SCHEMBL5277630 | 0.77 | HCAR2 (0.42) | HCAR2HCAR3HRH3 | |
| SCHEMBL5275090 | 0.77 | HCAR2 (0.46) | HCAR2HCAR3HRH3 | |
| SCHEMBL5281924 | 0.77 | HCAR2 (0.39) | HCAR2HCAR3HRH3PBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2064180-B1 | 4,5-RING ANNULATED INDOLE DERIVATIVES FOR TREATING OR PREVENTING OF HCV AND RELATED VIRAL INFECTIONS | MERCK SHARP & DOHME (US) | 2016-07-13 | — | — | EP | disclosed |
| EP-1859781-A2 | Brightening and/or colouring agent with triazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |