SCHEMBL527673

SCHEMBL527673

CN(C)OC(=O)CCCCN

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM6B O15054 1/20 0.54
KDM5C P41229 1/20 0.54
EGLN1 Q9GZT9 1/20 0.54
PHF8 Q9UPP1 1/20 0.54
KDM2A Q9Y2K7 1/20 0.54
CYP1A2 P05177 3/20 0.47
PAOX Q6QHF9 4/20 0.46
CYP2D6 P10635 1/20 0.44
NFKB1 P19838 1/20 0.44
BLM P54132 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
LMNA P02545 2/20 0.43
THRB P10828 2/20 0.43
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
PLG P00747 1/20 0.43
ALOX15 P16050 1/20 0.43
SLC6A2 P23975 1/20 0.43
RECQL P46063 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL27563676 0.98 KDM6B (0.52) KDM6BKDM5CEGLN1PHF8KDM2A
SCHEMBL27401158 0.93 KDM6B (0.56) KDM6BKDM5CEGLN1PHF8KDM2A
SCHEMBL1427252 0.89 KDM6B (0.65) KDM6BKDM5CEGLN1PHF8KDM2A
SCHEMBL6869117 0.86 KDM6B (0.62) KDM6BKDM5CEGLN1PHF8KDM2A
SCHEMBL29111710 0.86 KDM6B (0.62) KDM6BKDM5CEGLN1PHF8KDM2A
SCHEMBL27714369 0.83 KDM6B (0.54) KDM6BKDM5CEGLN1PHF8KDM2A
SCHEMBL219326 0.80 KDM6B (0.56) KDM6BKDM5CEGLN1PHF8KDM2A
SCHEMBL555756 0.78 DGKA (0.57) KDM6BKDM5CEGLN1PHF8KDM2A
SCHEMBL1671758 0.78 DGKA (0.57) KDM6BKDM5CEGLN1PHF8KDM2A
SCHEMBL1671499 0.78 DGKA (0.57) KDM6BKDM5CEGLN1PHF8KDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109069368-A HYDROPHILIC SILANES 美国陶氏有机硅公司 2018-12-21 CN disclosed
CN-104136498-B Novel liquid organopolysiloxanes and use thereof 道康宁东丽株式会社 2017-06-20 CN disclosed
EP-2658899-A1 COSMETIC CONTAINING LIQUID ORGANOPOLYSILOXANE Dow Corning Toray Co., Ltd. (JP) 2013-11-06 EP disclosed
EP-2598113-A1 COSMETIC FOR HAIR CONTAINING CO-MODIFIED ORGANOPOLYSILOXANE Dow Corning Toray Co., Ltd. (JP) 2013-06-05 EP disclosed
EP-2598112-A1 COSMETIC FOR HAIR CONTAINING SUGAR ALCOHOL-MODIFIED SILICONE Dow Corning Toray Co., Ltd. (JP) 2013-06-05 EP disclosed
EP-2563327-A1 POWDER TREATMENT AGENT COMPRISING SUGAR ALCOHOL -MODIFIED ORGANOPOLYSILOXANE Dow Corning Toray Co., Ltd. (JP) 2013-03-06 EP disclosed
EP-2563844-A1 ORGANOPOLYSILOXANE AND USE THEREOF AS SURFACTANT, POWDER TREATMENT AGENT, THICKENING AGENT OF OIL -BASED RAW MATERIAL OR GELLING AGENT. GEL AND EMULSION COMPOSITIONS, AS WELL AS, PREPARATIONS FOR EXTERNAL USE AND COSMETICS COMPRISING THE SAME Dow Corning Toray Co., Ltd. (JP) 2013-03-06 EP disclosed
WO-2012091155-A1 COSMETIC CONTAINING LIQUID ORGANOPOLYSILOXANE DOW CORNING TORAY CO., LTD. (JP) 2012-07-05 WO disclosed
WO-2012015070-A1 COSMETIC FOR HAIR CONTAINING CO-MODIFIED ORGANOPOLYSILOXANE DOW CORNING TORAY CO., LTD. (JP) 2012-02-02 WO disclosed
WO-2012015069-A1 COSMETIC FOR HAIR CONTAINING SUGAR ALCOHOL-MODIFIED SILICONE DOW CORNING TORAY CO., LTD. (JP) 2012-02-02 WO disclosed
WO-2011136394-A1 POWDER TREATMENT AGENT COMPRISING SUGAR ALCOHOL -MODIFIED ORGANOPOLYSILOXANE DOW CORNING TORAY CO., LTD. (JP) 2011-11-03 WO disclosed
WO-2011136393-A1 ORGANOPOLYSILOXANE AND USE THEREOF AS SURFACTANT, POWDER TREATMENT AGENT, THICKENING AGENT OF OIL -BASED RAW MATERIAL OR GELLING AGENT. GEL AND EMULSION COMPOSITIONS, AS WELL AS, PREPARATIONS FOR EXTERNAL USE AND COSMETICS COMPRISING THE SAME DOW CORNING TORAY CO., LTD. (JP) 2011-11-03 WO disclosed