SCHEMBL5277374

SCHEMBL5277374

CCCCCCn1nnc(C(Cl)(Cl)C(Cl)(Cl)Cl)c1F

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 4/20 0.40
HCAR3 P49019 1/20 0.32
SMPD1 P17405 4/20 0.31
MAPT P10636 1/20 0.31
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
GRM2 Q14416 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5280955 0.94 SLC9A1 (0.37) SLC9A1HCAR3GRM2
SCHEMBL5282682 0.88 SLC9A1 (0.42) SLC9A1HCAR3SMPD1MAPTALDH1A1
SCHEMBL5278259 0.87 SLC9A1 (0.34) SLC9A1ALDH1A1GRM2
SCHEMBL5279961 0.83 SLC9A1 (0.41) SLC9A1HCAR3SMPD1MAPTALDH1A1
SCHEMBL5278425 0.83 SLC9A1 (0.41) SLC9A1HCAR3SMPD1MAPTALDH1A1
SCHEMBL5279836 0.83 SLC9A1 (0.41) SLC9A1HCAR3SMPD1MAPTALDH1A1
SCHEMBL5281402 0.83 SLC9A1 (0.43) SLC9A1HCAR3SMPD1MAPTALDH1A1
SCHEMBL5277103 0.83 SLC9A1 (0.43) SLC9A1HCAR3SMPD1MAPTALDH1A1
SCHEMBL5276110 0.82 SLC9A1 (0.38) SLC9A1HCAR3SMPD1MAPT
SCHEMBL5280852 0.82 SLC9A1 (0.40) SLC9A1HCAR3SMPD1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859781-A2 Brightening and/or colouring agent with triazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed