SCHEMBL52778

SCHEMBL52778

CCCCCCCC/C=C\CCCCCCCCCCCCC(O)(C[N+](C)(C)C)P(=O)(O)O

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ GGPS1 O95749 8/20 0.51
▸ FDPS P14324 10/20 0.49
▸ LPAR3 Q9UBY5 3/20 0.44
▸ SMPD1 P17405 2/20 0.44
▸ LPAR1 Q92633 2/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ FAAH O00519 1/20 0.44
▸ TP53 P04637 1/20 0.44
▸ CYP1A2 P05177 1/20 0.44
▸ CYP3A4 P08684 1/20 0.44
▸ CYP2C19 P33261 1/20 0.44
▸ SOAT1 P35610 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ LPAR2 Q9HBW0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL52495 1.00 GGPS1 (0.51) GGPS1FDPSLPAR3SMPD1LPAR1
SCHEMBL7807607 1.00 GGPS1 (0.51) GGPS1FDPSLPAR3SMPD1LPAR1
SCHEMBL53191 1.00 GGPS1 (0.51) GGPS1FDPSLPAR3SMPD1LPAR1
SCHEMBL54443 1.00 GGPS1 (0.51) GGPS1FDPSLPAR3SMPD1LPAR1
SCHEMBL53735 1.00 GGPS1 (0.51) GGPS1FDPSLPAR3SMPD1LPAR1
SCHEMBL53611 1.00 GGPS1 (0.51) GGPS1FDPSLPAR3SMPD1LPAR1
SCHEMBL52996 1.00 GGPS1 (0.51) GGPS1FDPSLPAR3SMPD1LPAR1
SCHEMBL52879 1.00 GGPS1 (0.51) GGPS1FDPSLPAR3SMPD1LPAR1
SCHEMBL52239 1.00 GGPS1 (0.51) GGPS1FDPSLPAR3SMPD1LPAR1
SCHEMBL53872 1.00 GGPS1 (0.51) GGPS1FDPSLPAR3SMPD1LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 403 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4363043-B1 COMPOSITIONS FOR USE IN METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS NOVOCURE GMBH (CH) 2026-04-22 — — EP claimed
US-12594421-B2 Compositions and methods for increasing cancer cell sensitivity to alternating electric fields NOVOCURE GMBH (CH) 2026-04-07 — — US claimed
US-20260053785-A1 COMBINATION THERAPY FOR TREATMENT OF CANCER PMV PHARMACEUTICALS INC (US) 2026-02-26 — — US claimed
US-20250339680-A1 COMPOSITIONS AND METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS NOVOCURE GMBH (CH) 2025-11-06 — — US claimed
EP-4615431-A1 COMBINATION THERAPIES FOR THE TREATMENT OF CANCER Astrazeneca AB (SE) 2025-09-17 — — EP claimed
EP-4604957-A1 COMBINATIONS OF A SERD FOR THE TREATMENT OF CANCER Astrazeneca AB (SE) 2025-08-27 — — EP claimed
US-20250205233-A1 EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) TYROSINE KINASE INHIBITORS IN COMBINATION WITH AN AKT INHIBITOR FOR THE TREATMENT OF CANCER ASTRAZENECA AB (SE) 2025-06-26 — — US claimed
US-20250171518-A1 METHODS FOR PREPARING CELLS FOR ADOPTIVE T CELL THERAPY CITY OF HOPE 2025-05-29 — — US claimed
WO-2025083205-A1 DRUG COMBINATION COMPRISING ANTI-CD37 ANTIBODY MAYTANSINE CONJUGATE AND BCL2 INHIBITOR OR PI3K INHIBITOR DEBIOPHARM INTERNATIONAL S.A. (CH) 2025-04-24 — — WO claimed
EP-4519418-A1 METHODS FOR IMPROVING T CELL EFFICACY Immatics US, Inc. (US) 2025-03-12 — — EP claimed
WO-2006121522-A2 IMPLANTABLE SENSORS AND PUMPS, ANTI-SCARRING AGENTS, AND THERAPEUTIC COMPOSITIONS ANGIOTECH INTERNATIONAL AG (CH) 2006-11-16 — — WO claimed
WO-2006118630-A2 PHOSPHOINOSITIDE MODULATION FOR THE TREATMENT OF ALZHEIMER'S DISEASE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2006-11-09 — — WO claimed
US-20050165245-A1 Phospholipid-analogous compounds MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2005-07-28 — — US claimed
US-20030083313-A1 Treatment of breast cancer with a liposome mixture comprising an antineoplastic alkylphospholipid and water- or lipid-soluble antiestrogen agents MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN (DE) 2003-05-01 — — US claimed
EP-1135193-B1 AGENTS PROVIDED FOR TREATING TUMORS, BASED ON LIPOSOMES, AND CONTAINING TAMOXIFEN MAX DELBRUECK CENTRUM (DE) 2002-10-30 — — EP claimed
EP-1135193-A1 AGENTS PROVIDED FOR TREATING TUMORS, BASED ON LIPOSOMES, AND CONTAINING TAMOXIFEN MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN (DE) 2001-09-26 — — EP claimed
WO-2000033917-A1 AGENTS PROVIDED FOR TREATING TUMORS, BASED ON LIPOSOMES, AND CONTAINING TAMOXIFEN Max-Delbrück-Centrum für Molekulare Medizin (DE) 2000-06-15 — — WO claimed
EP-0507337-B1 Novel erucyl, brassidyl and nervonyl derivatives MAX PLANCK GESELLSCHAFT (DE) 1996-10-23 — — EP claimed
US-5436234-A Treatment of protozoal and fungal diseases, autoimmune diseases and bone marrow damage MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG (DE) 1995-07-25 — — US claimed
EP-0507337-A2 Novel erucyl, brassidyl and nervonyl derivatives Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 1992-10-07 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260053785-A1 COMBINATION THERAPY FOR TREATMENT OF CANCER TP53, PI4K2A, PIK3CA GGPS1 1852/4885FDPS 2820/4885LPAR3 870/4885
US-20250171518-A1 METHODS FOR PREPARING CELLS FOR ADOPTIVE T CELL THERAPY CD4, ICOS, CD2 GGPS1 3741/4885FDPS 4490/4885LPAR3 1082/4885
US-12594421-B2 Compositions and methods for increasing cancer cell sensitivity to alternating electric fields PTK2, GSK3B, MTOR GGPS1 2636/4885FDPS 2709/4885LPAR3 1885/4885
US-20250205233-A1 EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) TYROSINE KINASE INHIBITORS IN COMBINATION WITH AN AKT INHIBITOR FOR THE TREATMENT OF CANCER EGFR, ERBB2, ERBB3 GGPS1 4052/4885FDPS 4278/4885LPAR3 1117/4885
US-20050165245-A1 Phospholipid-analogous compounds PHOSPHO1, SGMS1, SGMS2 GGPS1 120/4885FDPS 358/4885LPAR3 127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback