SCHEMBL5278971

SCHEMBL5278971

CCc1c(Cl)nnn1CC

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 1/20 0.35
GRIA1 P42261 1/20 0.35
GRIA2 P42262 1/20 0.35
GRIA3 P42263 1/20 0.35
GRIA4 P48058 1/20 0.35
NPC1 O15118 1/20 0.34
ALDH1A1 P00352 1/20 0.32
GRM2 Q14416 1/20 0.32
TOP2A P11388 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31332963 0.84 SLC9A1 (0.34) SLC9A1GRIA1GRIA2GRIA3GRIA4
SCHEMBL31333003 0.83 GRIA1 (0.37) SLC9A1GRIA1GRIA2GRIA3GRIA4
SCHEMBL5280687 0.83 SLC9A1 (0.33) SLC9A1GRIA1GRIA2GRIA3GRIA4
SCHEMBL5285294 0.83 SLC9A1 (0.39) SLC9A1GRIA4ALDH1A1GRM2TOP2A
SCHEMBL5279736 0.79 GRIA1 (0.38) SLC9A1GRIA1GRIA2GRIA3GRIA4
SCHEMBL5277992 0.79 GRIA1 (0.32) SLC9A1GRIA1GRIA2GRIA3GRIA4
SCHEMBL5281268 0.79 SLC9A1 (0.42) SLC9A1GRIA4ALDH1A1GRM2TOP2A
SCHEMBL5275132 0.79 MAOB (0.32) SLC9A1GRIA1GRIA2GRIA3GRIA4
SCHEMBL5281159 0.77 SLC9A1 (0.45) SLC9A1ALDH1A1GRM2
SCHEMBL5280867 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859781-A2 Brightening and/or colouring agent with triazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed