SCHEMBL5278992

SCHEMBL5278992

[CH2]c1cc(OCCCCCCCC)c([CH2])cc1OCCCCCCCC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 2/20 0.42
NR5A1 Q13285 1/20 0.42
MEN1 O00255 1/20 0.42
NR1I2 O75469 1/20 0.42
LMNA P02545 1/20 0.42
CHRM2 P08172 1/20 0.42
CYP3A4 P08684 1/20 0.42
ADRA2A P08913 1/20 0.42
MAPT P10636 1/20 0.42
OPRK1 P41145 1/20 0.42
HTR2B P41595 1/20 0.42
SLC6A3 Q01959 1/20 0.42
KMT2A Q03164 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
PLA2G2A P14555 1/20 0.42
TSHR P16473 1/20 0.42
CHUK O15111 1/20 0.41
DAPK3 O43293 1/20 0.41
JAK2 O60674 1/20 0.41
ROCK2 O75116 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2093715 0.96 SMPD1 (0.41) TLR8NR5A1MEN1NR1I2LMNA
SCHEMBL5284449 0.92 SMPD1 (0.46) SMPD1ESR1
SCHEMBL6002984 0.81 TLR8 (0.55) TLR8MEN1NR1I2LMNACHRM2
SCHEMBL28645328 0.81 NR5A1 (0.51) NR5A1TSHRPTPN11
SCHEMBL15404359 0.81 NR5A1 (0.51) NR5A1TSHRPTPN11
SCHEMBL2094045 0.81 NR5A1 (0.51) NR5A1TSHRPTPN11
SCHEMBL19549600 0.81 NR5A1 (0.51) NR5A1TSHRPTPN11
SCHEMBL3992140 0.80 SMN1; SMN2 (0.49) MEN1LMNAMAPTKMT2ACHUK
SCHEMBL5251026 0.79 NR5A1 (0.49) NR5A1TSHR
SCHEMBL2017879 0.78 THRA (0.41) TLR8NR5A1MEN1NR1I2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0901174-B1 Polymer light emitting device SUMITOMO CHEMICAL CO (JP) 2007-12-19 EP disclosed
US-6841269-B2 Hole transporting polymer and organic electroluminescence device using the same SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2005-01-11 US disclosed
US-20030211358-A1 Hole transporting polymer and organic electroluminescence device using the same SUMITOMO CHEMICAL COMPANY, LTD. 2003-11-13 US disclosed
EP-0893485-B1 Hole transporting polymer and organic electroluminescence device SUMITOMO CHEMICAL CO (JP) 2003-06-11 EP disclosed
US-6544670-B1 Durability and film-forming properties SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2003-04-08 US disclosed
US-6403236-B1 FLUORESCENT POLYMER CONTAINING UNSATURATED AROMATIC MONOMER AND CHARGE TRANSPORTING LAYER; STABILITY ON DRIVING; DURABILITY SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-06-11 US disclosed
EP-0901174-A2 Polymer light emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-10 EP disclosed
EP-0893485-A1 Hole transporting polymer and organic electroluminescence device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-01-27 EP disclosed