SCHEMBL5279481

SCHEMBL5279481

CC(C)=N/N=c1/sc2c(S(=O)(=O)O)cccc2n1C

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.38
MAPT P10636 5/20 0.38
NPC1 O15118 4/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
HTT P42858 2/20 0.38
KMT2A Q03164 4/20 0.36
MEN1 O00255 2/20 0.36
KCNQ3 O43525 2/20 0.35
KCNQ2 O43526 2/20 0.35
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C19 P33261 1/20 0.32
MYC P01106 1/20 0.31
GAA P10253 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5279486 1.00 RAB9A (0.38) RAB9AMAPTNPC1SMN1; SMN2HTT
SCHEMBL4615356 0.83 RAB9A (0.38) RAB9AMAPTNPC1SMN1; SMN2KMT2A
SCHEMBL4615357 0.83 RAB9A (0.38) RAB9AMAPTNPC1SMN1; SMN2KMT2A
SCHEMBL5282916 0.80 NPC1 (0.38) RAB9AMAPTNPC1SMN1; SMN2HTT
SCHEMBL5282918 0.80 NPC1 (0.38) RAB9AMAPTNPC1SMN1; SMN2HTT
SCHEMBL5277842 0.79 MAPT (0.40) RAB9AMAPTNPC1SMN1; SMN2HTT
SCHEMBL5277846 0.79 MAPT (0.40) RAB9AMAPTNPC1SMN1; SMN2HTT
SCHEMBL5283929 0.77 NPSR1 (0.43) RAB9AMAPTNPC1SMN1; SMN2HTT
SCHEMBL5283925 0.77 NPSR1 (0.43) RAB9AMAPTNPC1SMN1; SMN2HTT
SCHEMBL5278390 0.72 MAPT (0.64) RAB9AMAPTNPC1SMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1599178-B1 MEANS AND METHOD FOR DYEING KERATIN FIBRES WELLA AG (DE) 2007-12-19 EP claimed
US-20060070190-A1 Means and method for dyeing keratin fibres KOYO SEIKO CO., LTD. (JP) 2006-04-06 US claimed
EP-1599178-A1 MEANS AND METHOD FOR DYEING KERATIN FIBRES Wella Aktiengesellschaft (DE) 2005-11-30 EP claimed
WO-2004078151-A1 MEANS AND METHOD FOR DYEING KERATIN FIBRES WELLA AKTIENGESELLSCHAFT (DE) 2004-09-16 WO claimed
EP-1599178-B1 MEANS AND METHOD FOR DYEING KERATIN FIBRES WELLA AG (DE) 2007-12-19 EP disclosed
US-7294151-B2 Means and method for dyeing keratin fibres WELLA AG (DE) 2007-11-13 US disclosed
US-20060070190-A1 Means and method for dyeing keratin fibres KOYO SEIKO CO., LTD. (JP) 2006-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060070190-A1 Means and method for dyeing keratin fibres KRT18, KLK5, KIT RAB9A 3143/4885MAPT 1807/4885NPC1 4843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.