Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5288806 | 1.00 | F10 (0.65) | F10 | |
| SCHEMBL5242964 | 0.88 | F10 (0.60) | F10 | |
| SCHEMBL5242708 | 0.87 | F10 (0.50) | F10 | |
| SCHEMBL5288801 | 0.86 | F10 (0.68) | F10 | |
| SCHEMBL5279880 | 0.86 | F10 (0.68) | F10 | |
| SCHEMBL5245387 | 0.85 | F10 (0.60) | F10 | |
| SCHEMBL5275478 | 0.83 | F10 (0.47) | F10 | |
| SCHEMBL5283242 | 0.83 | F10 (0.45) | F10 | |
| SCHEMBL4638229 | 0.81 | F10 (0.66) | F10 | |
| SCHEMBL5324751 | 0.79 | F10 (0.65) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1869010-A1 | 3-SULFONYLAMINO-PYRROLIDINE-2-ONE DERIVATIVES AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006108709-A1 | 3-SULFONYLAMINO-PYRROLIDINE-2-ONE DERIVATIVES AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-10-19 | — | — | WO | disclosed |