Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.37 |
| ▸ | TYMP | P19971 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
| ▸ | POLG | P54098 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28677450 | 0.86 | FGFR1 (0.54) | FGFR1SLC22A6HPRT1TYMPCYP3A4 | |
| SCHEMBL14645672 | 0.86 | FGFR1 (0.54) | FGFR1SLC22A6HPRT1TYMPCYP3A4 | |
| SCHEMBL5065338 | 0.86 | FGFR1 (0.54) | FGFR1SLC22A6HPRT1TYMPCYP3A4 | |
| SCHEMBL16037340 | 0.84 | FGFR1 (0.55) | FGFR1SLC22A6HPRT1TYMPCYP3A4 | |
| SCHEMBL8896084 | 0.84 | FGFR1 (0.55) | FGFR1SLC22A6HPRT1TYMPCYP3A4 | |
| SCHEMBL8895343 | 0.83 | FGFR1 (0.54) | FGFR1SLC22A6HPRT1TYMPCYP3A4 | |
| SCHEMBL12658010 | 0.81 | FGFR1 (0.41) | FGFR1SLC22A6NT5EPOLA1 | |
| SCHEMBL14816681 | 0.81 | FGFR1 (0.41) | FGFR1SLC22A6NT5EPOLA1 | |
| SCHEMBL7262516 | 0.79 | FGFR1 (0.72) | FGFR1SLC22A6HPRT1TYMPCYP3A4 | |
| SCHEMBL7262522 | 0.79 | FGFR1 (0.72) | FGFR1SLC22A6HPRT1TYMPCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006076015-A3 | 1-[2-(PHOSPHONOMETHOXY)ETHYL]-CYTOSINE AND ANALOGS THEREOF | UNIV CALIFORNIA (US) | 2007-02-22 | — | — | WO | disclosed |
| WO-2006076015-A2 | 1-[2-(PHOSPHONOMETHOXY)ETHYL]-CYTOSINE AND ANALOGS THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-07-20 | — | — | WO | disclosed |
| WO-2006076015-A2 | 1-[2-(PHOSPHONOMETHOXY)ETHYL]-CYTOSINE AND ANALOGS THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-07-20 | — | — | WO | disclosed |