SCHEMBL5280106

SCHEMBL5280106

NC1C=CC=CC1(F)I

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9434282 0.72
SCHEMBL1989509 0.72
SCHEMBL1441894 0.72
SCHEMBL21830193 0.70
SCHEMBL1775067 0.70
SCHEMBL29262189 0.70
SCHEMBL6341539 0.70
SCHEMBL1459722 0.70
Iodide SCHEMBL29198705 0.68
Bromide SCHEMBL29198604 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228480-A1 PROCESSES FOR PREPARING PYRROLOPYRIDINE-ANILINE COMPOUNDS CURIA GLOBAL, INC. 2024-07-11 US disclosed
EP-4281069-A1 PROCESSES FOR PREPARING PYRROLOPYRIDINE-ANILINE COMPOUNDS NFlection Therapeutics, Inc. (US) 2023-11-29 EP disclosed
CN-117136056-A Process for preparing pyrrolopyridine-anilines 恩福莱克逊治疗有限公司 2023-11-28 CN disclosed
CN-110845439-B Method for synthesizing 2-substituted benzothiazole by one-pot method 南京工业大学 2023-04-11 CN disclosed
WO-2013036232-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF MYELOPROLIFERATIVE DISEASES AND OTHER PROLIFERATIVE DISEASES DECIPHERA PHARMACEUTICALS, LLC (US) 2013-03-14 WO disclosed
EP-1857440-A1 Novel compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and pharmaceutical compositions containing the same Amorepacific Corporation (KR) 2007-11-21 EP disclosed
WO-2007120012-A1 NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AMOREPACIFIC CORPORATION (KR) 2007-10-25 WO disclosed