Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2858226 | 1.00 | ALDH1A1 (0.55) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL2756235 | 1.00 | ALDH1A1 (0.55) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL10473440 | 0.92 | ALDH1A1 (0.48) | ALDH1A1USP2TSHR | |
| SCHEMBL14779634 | 0.89 | ALDH1A1 (0.50) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL2756236 | 0.89 | ALDH1A1 (0.50) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL14778728 | 0.87 | ALDH1A1 (0.48) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL14780210 | 0.87 | ALDH1A1 (0.48) | ALDH1A1USP2TSHRKDM4ELMNA | |
| SCHEMBL31456089 | 0.87 | ALDH1A1 (0.48) | ALDH1A1USP2TSHR | |
| SCHEMBL28760408 | 0.87 | ALDH1A1 (0.48) | ALDH1A1USP2TSHRCA1CA2 | |
| SCHEMBL4446331 | 0.87 | ALDH1A1 (0.48) | ALDH1A1USP2TSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1864990-A1 | Preparation of secondary phosphines | Universität Wien (AT) | 2007-12-12 | — | — | EP | disclosed |
| EP-1864990-A1 | Preparation of secondary phosphines | Universität Wien (AT) | 2007-12-12 | — | — | EP | disclosed |
| WO-2007137319-A2 | PREPARATION OF SECONDARY PHOSPHINES | Universität Wien (AT) | 2007-12-06 | — | — | WO | disclosed |
| EP-0582668-B1 | CHIRAL TRIDENTATE BIS(PHOSPHOLANE) LIGANDS | DU PONT (US) | 1997-11-19 | — | — | EP | disclosed |
| EP-0528865-B1 | CHIRAL PHOSPHOLANE TRANSITION METAL CATALYSTS | DU PONT (US) | 1995-01-11 | — | — | EP | disclosed |
| US-5322956-A | Enantioselective hydrogenation of unsaturated compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-06-21 | — | — | US | disclosed |
| US-5258553-A | Chiral tridentate bis(phospholane) ligands | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1993-11-02 | — | — | US | disclosed |
| US-5206398-A | For enantioselective hydrogenation | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-04-27 | — | — | US | disclosed |
| US-5202493-A | CHIRAL TRIDENTATE BIS(PHOSPHOLANE) LIGANDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-04-13 | — | — | US | disclosed |
| EP-0528865-A1 | CHIRAL PHOSPHOLANE TRANSITION METAL CATALYSTS. | DU PONT (US) | 1993-03-03 | — | — | EP | disclosed |
| US-5177230-A | Chiral phospholane transistor metal catalysts | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-01-05 | — | — | US | disclosed |
| WO-1991017998-A1 | CHIRAL PHOSPHOLANE TRANSITION METAL CATALYSTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-11-28 | — | — | WO | disclosed |
| US-5008457-A | Enantioselective hydrogenation of unsaturated compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-04-16 | — | — | US | disclosed |