SCHEMBL5280320

SCHEMBL5280320

O=C(n1cnnn1)n1nnnc1Cl

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KCNJ1 P48048 2/20 0.30
F2 P00734 1/20 0.30
NOTUM Q6P988 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5277085 0.79 KCNJ1 (0.30) KCNJ1
SCHEMBL5275093 0.79 HMGCR (0.31) KCNJ1
SCHEMBL5279141 0.79
SCHEMBL5274284 0.76
SCHEMBL5276975 0.76 NOTUM (0.32) KCNJ1NOTUM
SCHEMBL5277314 0.76 DAGLA (0.34) KCNJ1
SCHEMBL5278040 0.74 KCNJ1 (0.36) KCNJ1
SCHEMBL5275312 0.73 MGLL (0.44)
SCHEMBL4502875 0.64
SCHEMBL707611 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859783-A1 Brightening and/or colouring agent comprising N, N'-carbonyldiazoles and/or analagogues thereof Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed