Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 14/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | DRD4 | P21917 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | DRD1 | P21728 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | FPR3 | P25089 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5398075 | 0.92 | ADRB2 (0.50) | ADRB2CHRM3DRD2DRD4DRD3 | |
| SCHEMBL5398084 | 0.92 | ADRB2 (0.50) | ADRB2CHRM3DRD2DRD4DRD3 | |
| SCHEMBL5393168 | 0.92 | ADRB2 (0.47) | ADRB2CHRM3DRD2DRD4DRD3 | |
| SCHEMBL5280173 | 0.91 | ADRB2 (0.48) | ADRB2CHRM3DRD2DRD4DRD3 | |
| SCHEMBL5280167 | 0.91 | ADRB2 (0.48) | ADRB2CHRM3DRD2DRD4DRD3 | |
| SCHEMBL5394742 | 0.89 | ADRB2 (0.47) | ADRB2CHRM3DRD2DRD4DRD3 | |
| SCHEMBL5394748 | 0.89 | ADRB2 (0.47) | ADRB2CHRM3DRD2DRD4DRD3 | |
| SCHEMBL5433683 | 0.88 | ADRB2 (0.45) | ADRB2DRD2DRD4DRD3DRD1 | |
| SCHEMBL14357339 | 0.88 | ADRB2 (0.57) | ADRB2DRD2DRD4DRD3ADRB1 | |
| SCHEMBL14357338 | 0.88 | ADRB2 (0.57) | ADRB2DRD2DRD4DRD3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497261-B1 | PHENETHANOLAMINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2007-12-19 | — | — | EP | disclosed |