SCHEMBL5280716

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5280714	1.00	CYP1A2 (0.50)	CYP1A2CYP2C19LMNAL3MBTL1MAPK1
	SCHEMBL5282307	0.82	RXFP1 (0.54)	LMNAL3MBTL1MAPK1RAB9AALDH1A1
	SCHEMBL5282302	0.82	RXFP1 (0.54)	LMNAL3MBTL1MAPK1RAB9AALDH1A1
	SCHEMBL5278190	0.81	L3MBTL1 (0.37)	CYP1A2CYP2C19LMNAL3MBTL1ALDH1A1
	SCHEMBL5278187	0.81	L3MBTL1 (0.37)	CYP1A2CYP2C19LMNAL3MBTL1ALDH1A1
	SCHEMBL5287646	0.77	RXFP1 (0.44)	LMNAL3MBTL1MAPK1SMN1; SMN2RXFP1
	SCHEMBL4616637	0.77	CYP1A2 (0.56)	CYP1A2CYP2C19LMNAL3MBTL1MAPK1
	SCHEMBL4616638	0.77	CYP1A2 (0.56)	CYP1A2CYP2C19LMNAL3MBTL1MAPK1
	SCHEMBL23728036	0.76	CYP1A2 (0.51)	CYP1A2CYP2C19LMNAL3MBTL1MAPK1
	SCHEMBL23728038	0.76	CYP1A2 (0.51)	CYP1A2CYP2C19LMNAL3MBTL1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.