Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 7/20 | 0.69 |
| ▸ | CA1 | P00915 | 1/20 | 0.68 |
| ▸ | CES2 | O00748 | 4/20 | 0.64 |
| ▸ | CES1 | P23141 | 4/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nonanoate SCHEMBL5590408 | 0.97 | FABP3 (0.72) | FABP3CA1CES2CES1NFKB1 | |
| Stearic Acid SCHEMBL9710145 | 0.97 | FABP3 (0.72) | FABP3CA1CES2CES1NFKB1 | |
| SCHEMBL8742990 | 0.97 | FABP3 (0.72) | FABP3CA1CES2CES1NFKB1 | |
| Stearic Acid SCHEMBL12487272 | 0.97 | FABP3 (0.72) | FABP3CA1CES2CES1NFKB1 | |
| Stearic Acid SCHEMBL5032895 | 0.97 | FABP3 (0.72) | FABP3CA1CES2CES1NFKB1 | |
| Heptadecanoic Acid SCHEMBL869938 | 0.97 | FABP3 (0.72) | FABP3CA1CES2CES1NFKB1 | |
| N-Octacosanoic Acid SCHEMBL945953 | 0.97 | FABP3 (0.72) | FABP3CA1CES2CES1NFKB1 | |
| Pentadecanoic Acid SCHEMBL870275 | 0.97 | FABP3 (0.72) | FABP3CA1CES2CES1NFKB1 | |
| Dodecanoate SCHEMBL914943 | 0.97 | FABP3 (0.72) | FABP3CA1CES2CES1NFKB1 | |
| Behenic Acid SCHEMBL1707610 | 0.97 | FABP3 (0.72) | FABP3CA1CES2CES1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858531-A1 | USE OF COPPER SILICATE FOR THE CONTROL OF HERPES INFECTIONS | CONVE LTD (AU) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006096937-A1 | USE OF COPPER SILICATE FOR THE CONTROL OF HERPES INFECTIONS | CONVE LTD (AU) | 2006-09-21 | — | — | WO | disclosed |