Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 17/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5284549 | 0.89 | MAPK14 (0.58) | MAPK14 | |
| SCHEMBL5282254 | 0.81 | MAPK14 (0.58) | MAPK14 | |
| SCHEMBL5303157 | 0.81 | HDAC1 (0.54) | MAPK14 | |
| SCHEMBL5283217 | 0.80 | MAPK14 (0.57) | MAPK14 | |
| SCHEMBL15712822 | 0.79 | CA9 (0.49) | — | |
| SCHEMBL5291388 | 0.78 | MAPK14 (0.52) | MAPK14 | |
| SCHEMBL5280548 | 0.78 | MAPK14 (0.56) | MAPK14 | |
| SCHEMBL2023743 | 0.76 | HDAC1 (0.55) | — | |
| SCHEMBL15712818 | 0.76 | MEN1 (0.43) | — | |
| SCHEMBL5284312 | 0.76 | MAPK14 (0.57) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007000337-A1 | BICYCLIC DERIVATIVES AS P38 KINASE INHIBITORS | PALAU PHARMA, S.A. (ES) | 2007-01-04 | — | — | WO | claimed |
| WO-2007000337-A1 | BICYCLIC DERIVATIVES AS P38 KINASE INHIBITORS | PALAU PHARMA, S.A. (ES) | 2007-01-04 | — | — | WO | disclosed |