Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.57 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5280862 | 0.80 | MAPK14 (0.55) | MAPK14 | |
| SCHEMBL5280548 | 0.80 | MAPK14 (0.56) | MAPK14 | |
| SCHEMBL3048771 | 0.77 | HDAC6 (0.50) | MAPK14 | |
| SCHEMBL5284312 | 0.76 | MAPK14 (0.57) | MAPK14 | |
| SCHEMBL5282254 | 0.74 | MAPK14 (0.58) | MAPK14 | |
| SCHEMBL5284549 | 0.72 | MAPK14 (0.58) | MAPK14 | |
| SCHEMBL2318552 | 0.72 | MAPK14 (1.00) | MAPK14MAPK13HSPB1HTR2AHTR2B | |
| SCHEMBL3053804 | 0.71 | HDAC6 (0.49) | MAPK14 | |
| SCHEMBL3058508 | 0.71 | MAPK14 (0.56) | MAPK14MAPK11 | |
| SCHEMBL20924128 | 0.71 | PRF1 (0.46) | HTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007000337-A1 | BICYCLIC DERIVATIVES AS P38 KINASE INHIBITORS | PALAU PHARMA, S.A. (ES) | 2007-01-04 | — | — | WO | claimed |
| WO-2007000337-A1 | BICYCLIC DERIVATIVES AS P38 KINASE INHIBITORS | PALAU PHARMA, S.A. (ES) | 2007-01-04 | — | — | WO | disclosed |