SCHEMBL5280930

SCHEMBL5280930

CC(C)=N/N=c1\sc2ccc([N+](=O)[O-])cc2n1C

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.50
KMT2A Q03164 6/20 0.50
MEN1 O00255 3/20 0.50
SMN1; SMN2 Q16637 5/20 0.48
RAB9A P51151 4/20 0.48
NPC1 O15118 4/20 0.48
ALDH1A1 P00352 1/20 0.48
HTT P42858 2/20 0.39
CYP1A2 P05177 2/20 0.36
LMNA P02545 1/20 0.36
POLB P06746 1/20 0.36
DYRK1A Q13627 1/20 0.36
CYP2C9 P11712 1/20 0.36
HPGD P15428 1/20 0.36
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5280934 1.00 MAPT (0.50) MAPTKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL5285681 0.90 RAB9A (0.57) MAPTKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL5285678 0.90 RAB9A (0.57) MAPTKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL4614027 0.81 MAPT (0.49) MAPTKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL4614030 0.81 MAPT (0.49) MAPTKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL5280076 0.78 MAPT (0.40) MAPTKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL5281140 0.76 MAPT (0.44) MAPTKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL4613926 0.75 MAPT (0.45) MAPTKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL5281427 0.75 MAPT (0.46) MAPTKMT2AMEN1SMN1; SMN2RAB9A
SCHEMBL5281425 0.75 MAPT (0.46) MAPTKMT2AMEN1SMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1599178-B1 MEANS AND METHOD FOR DYEING KERATIN FIBRES WELLA AG (DE) 2007-12-19 EP claimed
US-20060070190-A1 Means and method for dyeing keratin fibres KOYO SEIKO CO., LTD. (JP) 2006-04-06 US claimed
EP-1599178-B1 MEANS AND METHOD FOR DYEING KERATIN FIBRES WELLA AG (DE) 2007-12-19 EP disclosed
US-7294151-B2 Means and method for dyeing keratin fibres WELLA AG (DE) 2007-11-13 US disclosed
US-20060070190-A1 Means and method for dyeing keratin fibres KOYO SEIKO CO., LTD. (JP) 2006-04-06 US disclosed
EP-1599178-A1 MEANS AND METHOD FOR DYEING KERATIN FIBRES Wella Aktiengesellschaft (DE) 2005-11-30 EP disclosed
WO-2004078151-A1 MEANS AND METHOD FOR DYEING KERATIN FIBRES WELLA AKTIENGESELLSCHAFT (DE) 2004-09-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060070190-A1 Means and method for dyeing keratin fibres KRT18, KLK5, KIT MAPT 1807/4885KMT2A 1273/4885MEN1 3322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.