Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 12/20 | 0.76 |
| ▸ | CCKBR | P32239 | 8/20 | 0.42 |
| ▸ | CCKAR | P32238 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321443 | 0.91 | PTH1R (0.64) | PTH1RCCKBRCCKAR | |
| SCHEMBL5278951 | 0.89 | PTH1R (0.62) | PTH1RCCKBRCCKAR | |
| SCHEMBL5319962 | 0.89 | PTH1R (0.62) | PTH1RCCKBRCCKAR | |
| SCHEMBL5323705 | 0.89 | PTH1R (0.79) | PTH1R | |
| SCHEMBL5320402 | 0.89 | PTH1R (0.62) | PTH1RCCKBR | |
| SCHEMBL5328885 | 0.88 | PTH1R (0.77) | PTH1RCCKBRCCKAR | |
| SCHEMBL5323683 | 0.88 | PTH1R (0.74) | PTH1RCCKBRCCKAR | |
| SCHEMBL5319569 | 0.88 | PTH1R (0.61) | PTH1RCCKBRCCKAR | |
| SCHEMBL5326270 | 0.87 | PTH1R (0.75) | PTH1RCCKBRCCKAR | |
| SCHEMBL5320309 | 0.87 | PTH1R (1.00) | PTH1RCCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190135890-A1 | FUSION PROTEINS OF COLLAGEN-BINDING DOMAIN AND PARATHYROID HORMONE | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2019-05-09 | — | — | US | disclosed |
| US-10202434-B2 | Fusion proteins of collagen-binding domain and parathyroid hormone | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2019-02-12 | — | — | US | disclosed |
| EP-3091075-B1 | FUSION PROTEINS OF COLLAGEN-BINDING DOMAIN AND PARATHYROID HORMONE | UNIV ARKANSAS (US) | 2018-06-13 | — | — | EP | disclosed |
| US-20170101457-A1 | FUSION PROTEINS OF COLLAGEN-BINDING DOMAIN AND PARATHYROID HORMONE | OCHSNER CLINIC FOUNDATION (US) | 2017-04-13 | — | — | US | disclosed |
| US-20170101457-A1 | FUSION PROTEINS OF COLLAGEN-BINDING DOMAIN AND PARATHYROID HORMONE | OCHSNER CLINIC FOUNDATION (US) | 2017-04-13 | — | — | US | disclosed |
| US-9528099-B2 | Fusion proteins of collagen-binding domain and parathyroid hormone | OCHSNER CLINIC FOUNDATION | 2016-12-27 | — | — | US | disclosed |
| US-9528099-B2 | Fusion proteins of collagen-binding domain and parathyroid hormone | OCHSNER CLINIC FOUNDATION | 2016-12-27 | — | — | US | disclosed |
| EP-3091075-A1 | FUSION PROTEINS OF COLLAGEN-BINDING DOMAIN AND PARATHYROID HORMONE | The Board of Trustees of The University of Arkansas (US) | 2016-11-09 | — | — | EP | disclosed |
| EP-2155874-B1 | FUSION PROTEINS OF COLLAGEN-BINDING DOMAIN AND PARATHYROID HORMONE | UNIV ARKANSAS (US) | 2016-05-11 | — | — | EP | disclosed |
| US-20150284701-A1 | FUSION PROTEINS OF COLLAGEN-BINDING DOMAIN AND PARATHYROID HORMONE | OCHSNER CLINIC FOUNDATION (US) | 2015-10-08 | — | — | US | disclosed |
| US-20150284701-A1 | FUSION PROTEINS OF COLLAGEN-BINDING DOMAIN AND PARATHYROID HORMONE | OCHSNER CLINIC FOUNDATION (US) | 2015-10-08 | — | — | US | disclosed |
| US-9062300-B2 | Fusion proteins of collagen-binding domain and parathyroid hormone | NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY (JP) | 2015-06-23 | — | — | US | disclosed |
| US-9062300-B2 | Fusion proteins of collagen-binding domain and parathyroid hormone | NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITY (JP) | 2015-06-23 | — | — | US | disclosed |
| US-8450273-B2 | Fusion proteins of collagen-binding domain and parathyroid hormone | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2013-05-28 | — | — | US | disclosed |
| US-8450273-B2 | Fusion proteins of collagen-binding domain and parathyroid hormone | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2013-05-28 | — | — | US | disclosed |
| US-20100129341-A1 | FUSION PROTEINS OF COLLAGEN-BINDING DOMAIN AND PARATHYROID HORMONE | OCHSNER CLINIC FOUNDATION | 2010-05-27 | — | — | US | disclosed |
| US-20100129341-A1 | FUSION PROTEINS OF COLLAGEN-BINDING DOMAIN AND PARATHYROID HORMONE | OCHSNER CLINIC FOUNDATION | 2010-05-27 | — | — | US | disclosed |
| WO-2008124166-A2 | FUSION PROTEINS OF COLLAGEN-BINDING DOMAIN AND PARATHYROID HORMONE | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2008-10-16 | — | — | WO | disclosed |
| WO-2006129120-A9 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-03-22 | — | — | WO | disclosed |
| WO-2006129120-A2 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2006-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100129341-A1 | FUSION PROTEINS OF COLLAGEN-BINDING DOMAIN AND PARATHYROID HORMONE | PTH1R, CALCRL, CALCR | PTH1R 1/4885CCKBR 1638/4885CCKAR 1636/4885 |
| US-20170101457-A1 | FUSION PROTEINS OF COLLAGEN-BINDING DOMAIN AND PARATHYROID HORMONE | PTH1R, CALCRL, CALCR | PTH1R 1/4885CCKBR 1638/4885CCKAR 1636/4885 |
| US-20150284701-A1 | FUSION PROTEINS OF COLLAGEN-BINDING DOMAIN AND PARATHYROID HORMONE | PTH1R, CALCRL, CALCR | PTH1R 1/4885CCKBR 1638/4885CCKAR 1636/4885 |
| US-20190135890-A1 | FUSION PROTEINS OF COLLAGEN-BINDING DOMAIN AND PARATHYROID HORMONE | PTH1R, CALCRL, CALCR | PTH1R 1/4885CCKBR 1638/4885CCKAR 1636/4885 |
| US-10202434-B2 | Fusion proteins of collagen-binding domain and parathyroid hormone | PTH1R, CALCRL, CALCR | PTH1R 1/4885CCKBR 1638/4885CCKAR 1636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.