Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 16/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5280948 | 0.89 | PTH1R (0.76) | PTH1RCCKBR | |
| SCHEMBL5323138 | 0.88 | PTH1R (0.81) | PTH1RALDH1A1ALDH2ALDH3A1CCKBR | |
| SCHEMBL5321708 | 0.88 | PTH1R (0.56) | PTH1RALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL5320943 | 0.86 | PTH1R (0.58) | PTH1R | |
| SCHEMBL5329426 | 0.85 | PTH1R (0.60) | PTH1RCCKBR | |
| SCHEMBL5323908 | 0.85 | PTH1R (0.60) | PTH1RCCKBR | |
| SCHEMBL5324210 | 0.85 | PTH1R (0.59) | PTH1RCCKBR | |
| SCHEMBL5324949 | 0.85 | PTH1R (0.57) | PTH1R | |
| SCHEMBL5324664 | 0.84 | PTH1R (0.58) | PTH1RCCKBR | |
| SCHEMBL5322494 | 0.84 | PTH1R (0.56) | PTH1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006129120-A9 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-03-22 | — | — | WO | disclosed |
| WO-2006129120-A2 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2006-12-07 | — | — | WO | disclosed |