SCHEMBL5281079

SCHEMBL5281079

CCCCC1(CCCC)N=NN=N1

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
LMNA P02545 1/20 0.33
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5280457 0.95 TSHR (0.35) TSHRLMNATHRB
SCHEMBL5277577 0.95 LMNA (0.30) TSHRLMNA
SCHEMBL5281063 0.92 TSHR (0.40) TSHRLMNATHRB
SCHEMBL5277353 0.92 TSHR (0.37) TSHRLMNATHRB
SCHEMBL5282819 0.89 TSHR (0.42) TSHRLMNATHRB
SCHEMBL3816629 0.89 LMNA (0.30) TSHRLMNA
SCHEMBL3820938 0.88
SCHEMBL5251011 0.85
SCHEMBL5274462 0.85 TSHR (0.38) TSHRLMNATHRB
SCHEMBL5275637 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859782-A1 Composition for coloring and/or lightening human hair comprising tetrazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed