Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20299307 | 0.87 | FFAR4 (0.44) | CYP4F2CYP4A11MEN1KMT2ARXRA | |
| SCHEMBL5287446 | 0.81 | MEN1 (0.40) | MEN1ALDH1A1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL22098534 | 0.80 | FFAR1 (0.48) | CYP4F2CYP4A11FFAR1MEN1ALDH1A1 | |
| SCHEMBL11902614 | 0.80 | HTR2A (0.49) | CYP4F2CYP4A11FFAR1ALDH1A1HTT | |
| SCHEMBL11902326 | 0.80 | HTR2A (0.49) | CYP4F2CYP4A11FFAR1ALDH1A1HTT | |
| SCHEMBL15541789 | 0.80 | HTR2A (0.49) | CYP4F2CYP4A11FFAR1ALDH1A1HTT | |
| SCHEMBL17385720 | 0.78 | CYP4F2 (0.44) | CYP4F2CYP4A11FFAR1GPR88 | |
| SCHEMBL1474158 | 0.78 | SLC6A2 (0.38) | MEN1ALDH1A1HTTBLMKMT2A | |
| SCHEMBL17386283 | 0.77 | CYP4F2 (0.41) | CYP4F2CYP4A11FFAR1GPR88HTR2A | |
| SCHEMBL11902519 | 0.77 | HTR2A (0.51) | CYP4F2CYP4A11FFAR1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866278-A1 | SUBSTITUTED ARYLOXOETHYL CYCLOPROPANECARBOXAMIDE COMPOUNDS AS VR1 RECEPTOR ANTAGONISTS | Pfizer, Inc. (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006103503-A1 | SUBSTITUTED ARYLOXOETHYL CYCLOPROPANECARBOXAMIDE COMPOUNDS AS VR1 RECEPTOR ANTAGONISTS | PFIZER JAPAN INC. (JP) | 2006-10-05 | — | — | WO | disclosed |