Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.58 |
| ▸ | HRH1 | P35367 | 2/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.58 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9543313 | 0.97 | HRH3 (0.59) | HRH3KCNH2SLC6A2HRH1CHRM2 | |
| SCHEMBL7436131 | 0.97 | HRH3 (0.58) | HRH3KCNH2SLC6A2HRH1CHRM2 | |
| SCHEMBL9543368 | 0.95 | HRH3 (0.56) | HRH3KCNH2SLC6A2HRH1CHRM2 | |
| SCHEMBL21037024 | 0.90 | HRH3 (0.62) | HRH3KCNH2SLC6A2HRH1CHRM2 | |
| SCHEMBL7346055 | 0.90 | HRH3 (0.55) | HRH3KCNH2SLC6A2HRH1CHRM2 | |
| SCHEMBL24059343 | 0.89 | HRH3 (0.60) | HRH3KCNH2SLC6A2HRH1CHRM2 | |
| SCHEMBL7887990 | 0.89 | HRH3 (0.60) | HRH3KCNH2SLC6A2HRH1CHRM2 | |
| SCHEMBL8361918 | 0.89 | HRH3 (0.60) | HRH3KCNH2SLC6A2HRH1CHRM2 | |
| SCHEMBL18024038 | 0.89 | HRH3 (0.53) | HRH3KCNH2SLC6A2HRH1CHRM2 | |
| SCHEMBL15510652 | 0.89 | HRH3 (0.53) | HRH3KCNH2SLC6A2HRH1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863486-A2 | TREATMENT OF EPILEPSY WITH NON-IMIDAZOLE ALKYLAMINES HISTAMINE H3-RECEPTOR LIGANDS | BIOPROJET (FR) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006103537-A2 | TREATMENT OF EPILEPSY WITH NON-IMIDAZOLE ALKYLAMINES HISTAMINE H3-RECEPTOR LIGANDS | BIOPROJET (FR) | 2006-10-05 | — | — | WO | disclosed |
| US-4146509-A | ORGANIC AMMONIUM COMPOUNDS USED AS POLYMERIZATION CATALYSTS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-27 | — | — | US | disclosed |