Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 15/20 | 0.48 |
| ▸ | EGLN2 | Q96KS0 | 4/20 | 0.46 |
| ▸ | THRA | P10827 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL966776 | 0.93 | EGLN1 (0.51) | EGLN1EGLN2THRATHRBKDM4E | |
| SCHEMBL967699 | 0.93 | EGLN1 (0.50) | EGLN1EGLN2THRATHRBKDM4E | |
| SCHEMBL967393 | 0.82 | EGLN1 (0.65) | EGLN1EGLN2THRATHRB | |
| SCHEMBL967020 | 0.82 | EGLN1 (0.65) | EGLN1EGLN2THRATHRB | |
| SCHEMBL969590 | 0.80 | EGLN1 (0.58) | EGLN1EGLN2 | |
| SCHEMBL968819 | 0.80 | EGLN1 (0.58) | EGLN1EGLN2 | |
| SCHEMBL966959 | 0.80 | EGLN1 (0.53) | EGLN1 | |
| SCHEMBL968156 | 0.76 | EGLN1 (0.48) | EGLN1 | |
| SCHEMBL2883326 | 0.76 | EGLN1 (0.48) | EGLN1THRATHRBKDM4EALDH1A1 | |
| SCHEMBL522758 | 0.74 | EGLN1 (0.84) | EGLN1EGLN2THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866318-A2 | THIENOPYRIDINE COMPOUNDS, AND METHODS OF USE THEREOF | FIBROGEN, INC. (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006094292-A2 | THIENOPYRIDINE COMPOUNDS, AND METHODS OF USE THEREOF | FIBROGEN, INC. (US) | 2006-09-08 | — | — | WO | disclosed |