Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 10/20 | 0.44 |
| ▸ | RAB9A | P51151 | 10/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.44 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5281927 | 1.00 | KMT2A (0.47) | KMT2ANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL4615819 | 0.81 | ALDH1A1 (0.50) | KMT2ANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL4615821 | 0.81 | ALDH1A1 (0.50) | KMT2ANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL5278396 | 0.80 | MAPT (0.64) | KMT2ANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL29774515 | 0.80 | MAPT (0.64) | KMT2ANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL5278390 | 0.80 | MAPT (0.64) | KMT2ANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL5283238 | 0.78 | MAPT (0.43) | KMT2ANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL5283235 | 0.78 | MAPT (0.43) | KMT2ANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL5282524 | 0.76 | NPSR1 (0.55) | KMT2ANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL5282522 | 0.76 | NPSR1 (0.55) | KMT2ANPC1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599178-B1 | MEANS AND METHOD FOR DYEING KERATIN FIBRES | WELLA AG (DE) | 2007-12-19 | — | — | EP | disclosed |
| US-7294151-B2 | Means and method for dyeing keratin fibres | WELLA AG (DE) | 2007-11-13 | — | — | US | disclosed |
| US-20060070190-A1 | Means and method for dyeing keratin fibres | KOYO SEIKO CO., LTD. (JP) | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060070190-A1 | Means and method for dyeing keratin fibres | KRT18, KLK5, KIT | KMT2A 1273/4885NPC1 4843/4885RAB9A 3143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.