Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PAM | P19021 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741684 | 0.86 | CYP3A4 (0.49) | CYP3A4CYP2C9CES1CES2AKR1B1 | |
| SCHEMBL5283363 | 0.82 | CYP3A4 (0.49) | CYP3A4CYP2C9CES1CES2AKR1B1 | |
| SCHEMBL28125867 | 0.79 | SMN1; SMN2 (0.46) | CYP3A4CYP2C9CES1CES2AKR1B1 | |
| SCHEMBL265270 | 0.79 | MEN1 (0.53) | CYP3A4CYP2C9CES1CES2AKR1B1 | |
| SCHEMBL8168086 | 0.78 | CYP3A4 (0.45) | CYP3A4CYP2C9CES1CES2AKR1B1 | |
| SCHEMBL8168085 | 0.78 | CYP3A4 (0.45) | CYP3A4CYP2C9CES1CES2AKR1B1 | |
| SCHEMBL367454 | 0.77 | CYP3A4 (0.66) | CYP3A4CYP2C9CES1CES2AKR1B1 | |
| SCHEMBL7923429 | 0.77 | CYP3A4 (0.66) | CYP3A4CYP2C9CES1CES2AKR1B1 | |
| SCHEMBL265774 | 0.77 | CYP3A4 (0.66) | CYP3A4CYP2C9CES1CES2AKR1B1 | |
| SCHEMBL4623853 | 0.77 | CES2 (0.45) | CES1CES2AKR1B1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1281516-B1 | Planographic printing plate precursor | FUJIFILM CORP (JP) | 2007-12-19 | — | — | EP | disclosed |
| US-6951171-B2 | Using graft polymer on etched or anodized aluminum substrate | FUJI PHOTO FILM CO., LTD. (JP) | 2005-10-04 | — | — | US | disclosed |
| US-20030129520-A1 | Using graft polymer on etched or anodized aluminum substrate | FUJIFILM CORPORATION (JP) | 2003-07-10 | — | — | US | disclosed |
| EP-1281516-A2 | Planographic printing plate precursor | FUJI PHOTO FILM CO., LTD. (JP) | 2003-02-05 | — | — | EP | disclosed |