Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 14/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | REN | P00797 | 2/20 | 0.48 |
| ▸ | CTRC | Q99895 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5282032 | 1.00 | CMA1 (0.57) | CMA1ACEKMT2ARENCTRC | |
| SCHEMBL8103315 | 0.88 | NTSR1 (0.49) | CMA1 | |
| SCHEMBL5275753 | 0.84 | DPP4 (0.51) | CMA1ACEKMT2A | |
| SCHEMBL5275743 | 0.84 | DPP4 (0.51) | CMA1ACEKMT2A | |
| SCHEMBL8112052 | 0.83 | CMA1 (0.47) | CMA1 | |
| SCHEMBL10404192 | 0.81 | CMA1 (0.53) | CMA1ACEKMT2AREN | |
| SCHEMBL5280818 | 0.81 | CMA1 (0.53) | CMA1ACEKMT2AREN | |
| SCHEMBL10404191 | 0.81 | CMA1 (0.53) | CMA1ACEKMT2AREN | |
| SCHEMBL8366869 | 0.80 | CMA1 (0.52) | CMA1ACEKMT2AREN | |
| SCHEMBL22961962 | 0.80 | ACE (0.72) | CMA1ACEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863804-A1 | INHIBITORS OF HISTONE DEACETYLASE | Methylgene, Inc. (CA) | 2007-12-12 | — | — | EP | disclosed |
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | disclosed |
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC3, HDAC11 | CMA1 1486/4885ACE 2939/4885KMT2A 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.