Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28093888 | 0.92 | KMT2A (0.58) | L3MBTL1TDP1KMT2ACNR1CNR2 | |
| SCHEMBL27965714 | 0.92 | ESR1 (0.51) | L3MBTL1TDP1KMT2AMEN1LMNA | |
| SCHEMBL10185057 | 0.83 | ALDH1A1 (0.58) | L3MBTL1TDP1KMT2AMEN1LMNA | |
| SCHEMBL384968 | 0.83 | ESR1 (0.58) | KMT2ACNR1CNR2ALDH1A1ESR1 | |
| SCHEMBL8594247 | 0.81 | TDP1 (0.47) | L3MBTL1TDP1KMT2ALMNAALDH1A1 | |
| SCHEMBL18547195 | 0.81 | HDAC4 (0.57) | L3MBTL1KMT2ACNR1CNR2ALDH1A1 | |
| SCHEMBL12424105 | 0.81 | HPGD (0.51) | L3MBTL1TDP1KMT2AACHE | |
| SCHEMBL4462758 | 0.81 | HDAC3 (0.57) | KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL8594253 | 0.81 | TDP1 (0.47) | L3MBTL1TDP1KMT2ALMNAALDH1A1 | |
| SCHEMBL3541681 | 0.81 | MEN1 (0.49) | L3MBTL1KMT2ACNR1CNR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007007347-A1 | INDUSTRIAL PROCESS OF FEXOFENADINE HYDROCHLORIDE WITH CONTROLLED SIDE PRODUCTS | WOCKHARDT LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |
| US-6436962-B1 | ALPHA 1A ADRENERGIC RECEPTOR ANTAGONISTS; RELIEF FROM BENIGN PROSTATIC HYPERPLASIA BY LESS HINDERED URINE FLOW BY RELAXING SMOOTH MUSCLE TISSUE; WITH A TESTOSTERONE 5-ALPHA REDUCTASE INHIBITOR, FINASTERIDE; ACUTE AND CHRONIC RELIEF | MERCK & CO., INC. | 2002-08-20 | — | — | US | disclosed |