Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4175159 | 0.87 | AR (0.46) | ARMAPTRAB9AMAPK1SIRT6 | |
| SCHEMBL14625835 | 0.79 | AR (0.37) | ARRAB9ASMN1; SMN2 | |
| SCHEMBL4172806 | 0.76 | ACHE (0.45) | ARMAPTMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL3047176 | 0.67 | CYP3A4 (0.56) | ARMAPTRAB9AMAPK1SIRT6 | |
| SCHEMBL14625278 | 0.67 | ACHE (0.44) | AR | |
| SCHEMBL3054200 | 0.66 | CYP3A4 (0.61) | ARMAPTRAB9AMAPK1SIRT6 | |
| SCHEMBL4184038 | 0.66 | TMEM97 (0.53) | ARMAPK1TMEM97ALDH1A1CYP3A4 | |
| SCHEMBL3058238 | 0.65 | CNR2 (0.43) | ARMAPK1SIRT6TMEM97ALDH1A1 | |
| SCHEMBL4595549 | 0.65 | AR (0.47) | ARMAPTALDH1A1LMNACYP2C9 | |
| Trifluoroacetic Acid SCHEMBL3419464 | 0.64 | AR (0.48) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007005887-A2 | ANDROGEN RECEPTOR MODULATOR COMPOUNDS, COMPOSITIONS AND USES THEREOF | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2007-01-11 | — | — | WO | claimed |