SCHEMBL5282883

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5282886	1.00	CYP2C9 (0.37)	CYP2C9CYP2C19KMT2ARECQLCYP1A2
	SCHEMBL5279506	0.86	KMT2A (0.40)	CYP2C9CYP2C19KMT2ARECQLCYP1A2
	SCHEMBL5283318	0.86	KMT2A (0.40)	CYP2C9CYP2C19KMT2ARECQLCYP1A2
	SCHEMBL5298274	0.82	ALDH1A1 (0.37)	CYP2C9CYP2C19KMT2ACYP1A2KDM4E
	SCHEMBL5298282	0.82	ALDH1A1 (0.37)	CYP2C9CYP2C19KMT2ACYP1A2KDM4E
	SCHEMBL5286269	0.79	PTGS1 (0.31)	KDM4EALDH1A1PTGS2LMNAPTGS1
	SCHEMBL5285754	0.79	PTGS1 (0.31)	KDM4EALDH1A1PTGS2LMNAPTGS1
	SCHEMBL4613865	0.77	ALDH1A1 (0.51)	CYP2C9CYP2C19KMT2ARECQLCYP1A2
	SCHEMBL4613861	0.77	ALDH1A1 (0.51)	CYP2C9CYP2C19KMT2ARECQLCYP1A2
	SCHEMBL5293037	0.77	MAPT (0.34)	KMT2ARECQLKDM4EMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.