Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.45 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5302865 | 0.86 | MAPK14 (0.43) | MAPK14THRATHRBALDH1A1HTT | |
| SCHEMBL4473137 | 0.81 | MAPK14 (0.60) | MAPK14THRATHRBALDH1A1HTT | |
| SCHEMBL4384374 | 0.75 | MAPK14 (0.68) | MAPK14BRD4PKMMAOAMAOB | |
| Bromide SCHEMBL4381438 | 0.73 | MAPK14 (0.66) | MAPK14BRD4PKMMAOAMAOB | |
| SCHEMBL3523144 | 0.73 | MAPK14 (0.46) | MAPK14ALDH1A1HTTSMN1; SMN2HPGD | |
| SCHEMBL16791957 | 0.73 | PTPN1 (0.46) | MAPK14ALDH1A1SMN1; SMN2BRD4PKM | |
| SCHEMBL2463311 | 0.73 | MAPK14 (0.48) | MAPK14BRD4MAOB | |
| Bromide SCHEMBL3522011 | 0.72 | MAPK14 (0.45) | MAPK14ALDH1A1HTTSMN1; SMN2HPGD | |
| SCHEMBL24719526 | 0.72 | CA2 (0.38) | ALDH1A1HTTSMN1; SMN2BRD4HPGD | |
| SCHEMBL4384840 | 0.71 | KMT2A (0.52) | MAPK14THRATHRBALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006591-A2 | DIHALOGENATION OF N,O-DISUBSTITUTED HYDROXIPYRIDONES AND USES THEREOF | BAYER CROPSCIENCE SA (FR) | 2007-01-18 | — | — | WO | claimed |