SCHEMBL5283830

SCHEMBL5283830

CCCn1nnc(C)c1C(Cl)(Cl)C(Cl)(Cl)Cl

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 1/20 0.35
CYP1A2 P05177 2/20 0.35
ALDH1A1 P00352 2/20 0.35
ADORA2A P29274 1/20 0.33
ADORA2B P29275 1/20 0.33
MEN1 O00255 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32
GRM2 Q14416 1/20 0.32
TOP2A P11388 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5276320 0.90 SLC9A1 (0.38) SLC9A1MEN1CYP2C19KMT2AGRM2
SCHEMBL5285138 0.87 SLC9A1 (0.41) SLC9A1ALDH1A1GRM2
SCHEMBL5281310 0.85 SLC9A1 (0.37) SLC9A1CYP1A2ALDH1A1ADORA2AADORA2B
SCHEMBL5288120 0.85 SLC9A1 (0.32) SLC9A1
SCHEMBL5281000 0.82 SLC9A1 (0.35) SLC9A1CYP1A2ALDH1A1GRM2TOP2A
SCHEMBL5273607 0.82 SLC9A1 (0.35) SLC9A1CYP1A2ALDH1A1MEN1CYP2C9
SCHEMBL5285302 0.81 SLC9A1 (0.34) SLC9A1CYP1A2ALDH1A1GRM2TOP2A
SCHEMBL5282921 0.81 SLC9A1 (0.34) SLC9A1CYP1A2ALDH1A1GRM2
SCHEMBL5277843 0.81 SLC9A1 (0.34) SLC9A1CYP1A2ALDH1A1GRM2
SCHEMBL5280830 0.81 GRM2 (0.37) SLC9A1CYP1A2ALDH1A1GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859781-A2 Brightening and/or colouring agent with triazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed