Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAF1 | P04049 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | BRAF | P15056 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529349 | 0.90 | MAPT (0.61) | MAPTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL529287 | 0.89 | KMT2A (0.64) | MAPTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL528754 | 0.88 | MAPT (0.56) | MAPTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL528344 | 0.88 | MAPT (0.56) | MAPTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL528820 | 0.88 | MAPT (0.56) | MAPTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL527890 | 0.86 | MAPT (0.62) | MAPTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL528788 | 0.85 | MAPT (0.54) | MAPTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL528757 | 0.85 | MAPT (0.54) | MAPTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL528337 | 0.84 | MAPT (0.56) | MAPTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL528058 | 0.84 | MEN1 (0.67) | MAPTNPSR1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |