Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.48 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528642 | 0.92 | LMNA (0.48) | MAPTNPSR1P2RY2GPR17CNR1 | |
| SCHEMBL528568 | 0.90 | CCR2 (0.47) | MAPTNPSR1P2RY2GPR17CNR1 | |
| SCHEMBL528483 | 0.89 | MAPT (0.54) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL527969 | 0.89 | MAPT (0.60) | MAPTKMT2AP2RY2GPR17ALDH1A1 | |
| SCHEMBL529349 | 0.87 | MAPT (0.61) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL529287 | 0.86 | KMT2A (0.64) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL527890 | 0.86 | MAPT (0.62) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL528820 | 0.85 | MAPT (0.56) | MAPTNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL528344 | 0.85 | MAPT (0.56) | MAPTNPSR1MEN1KMT2AGPR17 | |
| SCHEMBL528395 | 0.85 | MAPT (0.56) | MAPTNPSR1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |