⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6670546 | 1.00 | CARM1 (0.33) | — | |
| SCHEMBL25769149 | 1.00 | CARM1 (0.33) | — | |
| SCHEMBL1092361 | 1.00 | — | — | |
| Bromide SCHEMBL7065182 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL28297139 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL1027109 | 0.97 | CARM1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL28745686 | 0.97 | CARM1 (0.32) | — | |
| SCHEMBL528887 | 0.96 | — | — | |
| SCHEMBL15388363 | 0.96 | — | — | |
| Bromide SCHEMBL4361146 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 485 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043617-B2 | 4-(N-methyl) aminopiperidine myricetin derivative containing dithiocarbamate, preparation method and application | GUIZHOU UNIVERSITY (CN) | 2024-07-23 | — | — | US | claimed |
| WO-2024102026-A1 | INHIBITORS OF HUMAN ALDOSTERONE SYNTHASE (CYP11B2) | «TARGET MEDICALS» LIMITED LIABILITY COMPANY (RU) | 2024-05-16 | — | — | WO | claimed |
| CN-112654620-B | Novel pyrazolopyridine compounds for the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2023-08-04 | — | — | CN | claimed |
| EP-3844159-B1 | NOVEL PYRROLIDINYL AMIDE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | HOFFMANN LA ROCHE (CH) | 2023-05-03 | — | — | EP | claimed |
| EP-3847173-B1 | NOVEL PYRAZOLOPYRIDINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | HOFFMANN LA ROCHE (CH) | 2023-04-12 | — | — | EP | claimed |
| CN-115745995-A | ATR inhibitors and uses thereof | 苏州浦合医药科技有限公司 | 2023-03-07 | — | — | CN | claimed |
| US-20220112187-A1 | PYRAZOLOPYRIDINE AMINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | HOFFMANN-LA ROCHE INC. (US) | 2022-04-14 | — | — | US | claimed |
| US-20210355122-A1 | PYRAZOLOPYRIDINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | HOFFMANN-LA ROCHE INC. (US) | 2021-11-18 | — | — | US | claimed |
| US-20210323977-A1 | PYRROLIDINYL AMIDE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | HOFFMANN-LA ROCHE INC. (US) | 2021-10-21 | — | — | US | claimed |
| EP-3849974-A1 | PYRAZOLOPYRIDINE AMINE COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | F. Hoffmann-La Roche AG (CH) | 2021-07-21 | — | — | EP | claimed |
| EP-2532659-A1 | Pyrimidinyl and 1,3,5-triazinyl benzimidazoles and their use in cancer therapy | Pathway Therapeutics, Inc. (US) | 2012-12-12 | — | — | EP | claimed |
| EP-2451802-A1 | PYRIMIDINYL AND 1,3,5-TRIAZINYL BENZIMIDAZOLES AND THEIR USE IN CANCER THERAPY | Pathway Therapeutics, Inc. (US) | 2012-05-16 | — | — | EP | claimed |
| US-20110009405-A1 | PYRIMIDINYL AND 1,3,5-TRIAZINYL BENZIMIDAZOLES AND THEIR USE IN CANCER THERAPY | PATHWAY THERAPEUTICS LIMITED (NZ) | 2011-01-13 | — | — | US | claimed |
| WO-2011005119-A1 | PYRIMIDINYL AND 1,3,5-TRIAZINYL BENZIMIDAZOLES AND THEIR USE IN CANCER THERAPY | PATHWAY THERAPEUTICS LIMITED (NZ) | 2011-01-13 | — | — | WO | claimed |
| US-20100190988-A1 | PROCESS FOR PREPARATION OF PYRAZOLE DERIVATIVES | SHAH DARMESH MAHENDRABHAI | 2010-07-29 | — | — | US | claimed |
| WO-2008102367-A1 | PROCESS FOR PREPARATION OF PYRAZOLE DERIVATIVES | SHAH DARMESH MAHENDRABHAI (IN) | 2008-08-28 | — | — | WO | claimed |
| CN-1479628-A | Use of CYP206 inhibitors in combination therapies | �Ʒ� | 2004-03-03 | — | — | CN | claimed |
| US-6503930-B1 | Treating cytokine-mediated diseases, such as inflammation | G.D. SEARLE & COMPANY | 2003-01-07 | — | — | US | claimed |
| EP-0925302-A1 | PALLADIUM CATALYZED INDOLIZATION | Merck & Co., Inc. (US) | 1999-06-30 | — | — | EP | claimed |
| WO-1998006725-A1 | PALLADIUM CATALYZED INDOLIZATION | MERCK & CO., INC. (US) | 1998-02-19 | — | — | WO | claimed |